Biochemistry - University of Arizona
Wegener 's granulomatosis is an immunologically mediated disease were anti-neutrophil cytoplasmic antibodies (ANCA) in serum correlate with disease activity and may protect proteases from inactivation by binding to their natural inhibitors. It presents as nodular densities on chest x-ray, hemoptysis, chest pain, fever, dyspnea, chronic sinusitis, and evidence of renal disease. Acute ... ................
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