Role of the Srs2-Rad51 Interaction Domain in Crossover ...
domain and embedded within a protein sequence resembling a BRC repeat motif. The srs2-F891A mutation leads to a complete loss of interaction with Rad51 as measured through yeast two-hybrid analysis and a partial loss of interaction as determined through protein pulldown assays with purified Srs2, Srs2-F891A, and Rad51 proteins. Even ................
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