Acids and Bases

Acids and Bases

Dr. Diala Abu-Hassan, DDS, PhD

Dr.abuhassand@

Lecture 1

MD summer 2014

science.

Dr. Diala Abu-Hassan

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Required material and further reading

Required:

Handout

Text books:

Biochemistry. Campbell Chapter 2

Fundamentals of General, Organic, and

Biological Chemistry. McMurry. Chapter 10

softcopy will be sent

Dr. Diala Abu-Hassan

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Outline

? Introduction- The Science of

Biochemistry

? Definitions of acids and bases

? Acid and base strength

? The dissociation constant

? Conjugate pair strength

? Water dissociation

Dr. Diala Abu-Hassan

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What is Biochemistry?

Biochemistry is the science

concerned with studying the

various molecules that occur in

living cells and organisms and

their chemical reactions.

Dr. Diala Abu-Hassan

Garret et4 al

Why Biochemistry is important to

Human Biology?

1. Biochemistry is an intrinsically beautiful and fascinating

body of knowledge. ¡°Lubert Stryer¡±

Because it unravels the details of the most fundamental

processes in biological systems.

2. Biochemistry massively influences medicine and

treatment development, ex. sickle-cell anemia, cystic

fibrosis, hemophilia, etc.

3. By advances in biochemistry, researchers can tackle

many questions in biology and medicine, ex. Biochemical

changes in diseases, causes of diseases, lab tests..etc.

Dr. Diala Abu-Hassan

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