Pharmacology: Basics for RNs
For example, if a drug is 20 mcg/mL and the ROE is 100 mcg/min, the clearance will be: CL = 100mcg/min / 20mcg/mL = 5 mL/min. Zero order kinetics (Linear) In zero order kinetics, the elimination rate is independent of the drug concentration but the half life (t1/2) depends on the initial drug concentration. Alcohol is eliminated by zero-order ... ................
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