University of Nebraska Medical Center



CURRICULUM VITAEAleem Siddique, MBBSCAMPUS ADDRESS: Department of Surgery-Cardiovascular&Thoracic Surg 982315 Nebraska Medical Center Omaha, NE 68198-2315 Phone: (402) 559-4424 Email: aleem.siddique@unmc.edu EDUCATION 1995 - 2000 MBBS, Medicine, Aga Khan University Medical CollegePOST DEGREE TRAINING 03/2001 - 05/2003 Research Fellow, Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA08/2003 - 06/2008 Residency, General Surgery, University of Texas Southwestern Medical center, Dallas, TX07/2009 - 06/2011 Residency, Cardiothoracic Surgery-Cardiothoracic Pathway, University of Arizona Health Sciences Center, Tucson, AZ10/2011 - 08/2013 Fellow, Cardiopulmonary Transplantation and Mechanical Circulatory Support, Freeman Hospital, Newcastle upon Tyne Hospital HGS Foundation Trust, UKACADEMIC APPOINTMENTS 2015- Present Surgical Director of Lung Transplantation, University of Nebraska Medical Center, Omaha, NE2013- PresentAssistant Professor, Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NECERTIFICATIONS AND LICENSES 2010 - 2020 Board Certified, American Board of Surgery 2012 - 2022 Board Certified, American Board of Thoracic Surgery2009 - 2011 Medical License, Arizona, 41213 2013 - PresentMedical License, Nebraska, 27514 GRANTS/CONTRACT SUPPORT SubmittedInternational Trial to Evaluate the Safety and Effectiveness of the Portable Organ CareSystem (OCS) Lung System for Recruiting, Preserving and Assessing Non-Ideal DonorLungs for Transplantation (EXPAND II Trial)Funding source: TransmedicsRole: Principal investigatorThe?Randomized?And Controlled?Noninferiority Trial to Evaluate Safety and?Clinical?Efficacy of the SurVeilTM?Drug-Coated Balloon iN?the Treatment of Subjects with Stenotic Lesions of the Femoropopliteal Artery Compared to the Medtronic IN.PACT? Admiral??Drug-Coated Balloon (TRANSCEND)Funding source: SurModics, Inc.2018- 2020Total Amount: $317,276 (Direct Cost: $252,425)Principal investigator: Andrew Goldsweig, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSGene and Stem Cell Therapy in Coronary Artery Bypass GraftFunding source: NIH 1R01HL128063-0103/13/2015– 02/28/2019 Total Amount: $2,903,260Principal investigator: Devendra Agrawal, PhD, Creighton UniversityCo-Investigator: Aleem Siddique, MBBSHeartMate IIIFunding source: Thoratec Corporation2015 – 2019Total Amount: $386,450 (Direct Cost: $307,377)Principal investigator: John Um, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSMulti-Center Study of MagLev Technology in Patients Undergoing MCS Therapy with Heartmate 3, Continued Access ProtocolFunding source: Thoratec Corporation2016 - 2019Total Amount: $480,017 (Direct Cost: $381,585)Principal investigator: John Um, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSNucleotidases in atherothrombosisFunding Agency: American Heart Association - National2018 - 2019Total Amount: $135,573 (Direct Cost: $53,248)Principal Investigator: Richard Gumina, M.D., Ph.D., University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSREmission from Stage D Heart Failure (RESTAGE-HF)Funding source: Thoratec Corporation2014 – 2019Total Amount: $50,751 (Direct Cost: $40,795)Principal investigator: Brian Lowes, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSA Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiac Surgery with Cardiopulmonary BypassFunding source: Grifols Worldwide Operations, Ltd.2014-2019Total Amount: $235,888 (Direct Cost: $187,883)Principal Investigator: Michael Moulton, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSA Double-blind, Randomized, Placebo-Controlled Study of Levosimendan in Patients with Left Ventricular Systopic Dysfunction Undergoing Cardiiac Surgery Requiring Cardiopulmonary Bypass (LEVO-CTS)Funding source: Tenax Therapeutics, Inc.2016 – 2017Total Amount: $45,755 (Direct Cost: $33,078)Principal Investigator: Ronald Zolty, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSCOMPASSIONATE USE: The SynCardia FreedomDriver System Study - Continued Access Policy (CAP) PhaseFunding Agency:SynCardia Systems, Inc.2013 - 2014Total Amount: $27,362 (Direct Cost: $22,232)Principal investigator: John Um, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSINTERNAL RESEARCH PROJECTSMid Term Results of LVAD ExchangeFunding source: Division of Cardiothoracic Surgery, University of Nebraska Medical Center2018- PresentRole: Principal investigatorA Retrospective Analysis of Aortic Dissection in NebraskaFunding source: Division of Cardiology, University of Nebraska Medical Center2018- PresentPrincipal investigator: Angela Yetman, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSExtra-Corporeal Membrane Oxygenation (ECMO) as a Bridge to Durable Left Ventricular Assist Device (LVAD)Funding source: Division of Cardiothoracic Surgery, University of Nebraska Medical Center2018- PresentPrincipal investigator: Marian Urban, MD, PhD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSFrailty, pain management and outcomes in end stage lung diseaseFunding source: Divisions of Cardiothoracic Surgery and Pulmonology, University of Nebraska Medical Center2017- PresentRole: Principal InvestigatorUNMC Lung Transplant Registry and BiorepositoryFunding source: Divisions of Cardiothoracic Surgery and Pulmonology, University of Nebraska Medical Center2016- PresentPrincipal investigator: Kristina Bailey, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSTitle: Assessment of Mortality, Risk Factors, and Outcomes in Patients Placed on Extracorporeal Membrane OxygenationFunding source: Division of Cardiothoracic Surgery, University of Nebraska Medical Center2015- PresentPrincipal investigator: HelenMari Merritt-Genore, DO, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSUNMC Heart Failure and Cardiac Transplant RegistryFunding source: Division of Cardiology, University of Nebraska Medical Center2015- PresentPrincipal investigator: Brian Lowes, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSAssessing outcomes of percutaneous RVAD placement for the treatment of right ventricular heart failureFunding source: Department of Anesthesiology, University of Nebraska Medical Center2014- PresentPrincipal investigator: Thomas Schulte, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSChanging Patterns in Extracorporeal Membrane Oxygenation (ECMO) Use at UNMC in the Last DecadeFunding source: Division of Pulmonology, University of Nebraska Medical Center2014- 2016Principal Investigator: Ji Hyun Rhee, MD, University of Nebraska Medical CenterCo-Investigator: Aleem Siddique, MBBSOTHER APPOINTMENTS OR POSITIONSOctober 2018Course Faculty ‘Advancing ECMO in our region and beyond’. Regional ECMO symposium, University of Nebraska Medical Center, Omaha, NE. July 2018- Present (2 year term)Member of United Network for Organ Sharing (UNOS) National Lung review BoardMay 2018- PresentResearch mentor for Collin McDonald, medical student, summer research projectApril 2018Symposium Design and Chair for ‘DCD Lungs- Expanding Utilization’ at the International Society of Heart and Lung Transplantation (ISHLT) 38th annual meeting and scientific sessions in Nice, FranceApril 2018Poster discussant for the International Society of Heart and Lung Transplantation (ISHLT) 38th annual meeting and scientific sessions in Nice, FranceMarch 2018Course Faculty ‘UNMC ECMO and Cardiopulmonary bypass Fellow’s Course’. National training course for ECMO/CPB hosted by University of Nebraska Medical Center, Omaha, NE.2017- 2018Member of the ISHLT task force for guidelines on the assessment and procurement of thoracic organs for transplant2017Abstract reviewer for the International Society of Heart and Lung Transplantation (ISHLT) 38th annual meeting and scientific sessions2016- PresentCourse presenter for the Cardiology Nursing Fellowship Program: Heart/Lung Transplantation at University of Nebraska Medical Center2015- PresentMentor for the High School Alliance job shadowing program2015- PresentCourse Director for Cardiothoracic Surgery Grand Rounds series2015Physician Leader for Complex ICU Clinical Effectiveness Initiative, Nebraska MedicineJanuary 2015Course Faculty ‘Advances in Cardiovascular Medicine’ regional conference hosted by University of Nebraska Medical Center, Omaha, NE.2014- PresentCourse Director for Cardiothoracic Surgery multi-disciplinary Journal Club2014- 2016Preceptor to medical student Apollo Stack for the longitudinal clinical experiences (LCE) program at University of Nebraska Medical Center2014- 2016Research mentor to Ji Hyun Rhee for her pulmonology fellowship research project on ECMO outcomes at UNMC2014- 2015Course director for Cardiothoracic Surgery Conference series 2013- 2015Cardiac Surgery Rotation, Surgery Clerkship, Team Education leader for medical students on the CT rotationCONSULTING POSITIONS2018- Consultant for Cryolife/Jotec for future aortic innovations2018- Consultant for Abbott for HeartMate future surgical innovations2015- Consultant for Pacira Pharmaceuticals for Liposomal Bupivacaine in Cardiothoracic SurgeryHONORS AND AWARDS 2012ISHLT International Traveling Scholarship Award to Melbourne, Australia1995-2000Bayer scholarship and Begum Shafiqua Zia-ul-Haq scholarship, Aga Khan University Medical College, Karachi, PakistanMEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES Parkland Surgical SocietyAmerican College of SurgeonsSociety of Thoracic SurgeonsInternational Society of Heart and Lung TransplantationCOMMITTEE ASSIGNMENTS 2018- PresentStructural Heart Quality and Mortality Committee, Nebraska MedicineChair: Michael Moulton, Gregory Pavlides2018- PresentInterventional/Structural Heart Disease-Focused TeamChair: Andrew Goldsweig2018- PresentVascular Disease Disease-Focused TeamChair: Jason Johanning2016- PresentECMO (ExtraCorporeal Membrane Oxygenation) Steering Committee, Nebraska MedicineChair: HelenMari Merritt-Genore2015- PresentLung transplant Patient Selection Committee, Nebraska MedicineChair: myself, Heather Strah2015- PresentSurgical Services Operations Committee (SSOC), Nebraska MedicineChair: Matthew Mormino2015- PresentProgram Evaluation Committee (PEC) for the Thoracic Surgery Residency Program, University of Nebraska Medical CenterChair: Rudy Lackner2015- PresentClinical Competencies Committee (CCC) for the Thoracic Surgery Residency Program, University of Nebraska Medical CenterChair: Rudy Lackner2013- PresentSolid Organ Transplant Quality Steering Committee (QAPI), Nebraska MedicineChair: Alan Langnas2013- PresentHeart transplant and Mechanical Circulatory Support Patient Selection Committee, Nebraska MedicineChair: Brian Lowes2013- PresentCardiac Surgery Quality Committee, Nebraska MedicineChair: Michael Moulton2016- 2017 (Committee replaced with Disease-Focused teams)Cardiothoracic Surgery Research CommitteeChair: Michael Moulton2015- 2017 (term completed)Patient Outcomes Committee, Nebraska MedicineChair: Micah BeachyPRESENTATIONS AT SCIENTIFIC MEETINGSSiddique A; Hinnebusch BF; Abedrapo MA; Zhang WY; Malo MS; Hodin RA. Convergence of the Thyroid Hormone and Gut-Enriched Kruppel-Like Factor Pathways in the Context of Enterocyte Differentiation. American College of Surgeons (ACS) 88th Annual Clinical Congress; 2002 Oct 6-11. San Francisco, CASiddique A; Malo MS; Zhang WY; Abedrapo MA; Henderson JW; Chen A; Mozumder M; Hodin RA. Multiple Potential Molecular Targets for Modulating Thyroid Hormone Action. American College of Surgeons (ACS) 89th Annual Clinical Congress; 2003 Jan. Chicago, ILSiddique A; Zogakis T. Retrospective Review of Rhabdomyocarcoma Presenting in Adult Patients and Report of a Rare Variant with Metastasis to the Soft Tissue. University of Texas Southwestern Medical Center Surgery Research Forum; 2008 JuneSiddique A; Clagett GP; Barnett CC. Retroperitoneal Paraganglioma Requiring Partial Vena Caval Resection. North Texas American College of Surgeons (ACS) Annual Meeting; 2008 FebSiddique A; Knoper SR; Raz Y; Coehlo-Anderson R; Wild J; Mineburg N; Daniel J; Moulton MJ. Recurrence of Bronchiolitis Obliterans may Limit Long-Term Outcomes in Lung Retransplantation. International Society for Heart and Lung Transplantation Annual Meeting; 2011 Apr 13-16. San Diego, CABose A; Siddique A; Ozalp F; Butt T; Dark JH; Clark SC. Management of Vascular Anastomotic Complications in Lung Transplantation. European Society for Heart and Lung Transplantation Symposium; 2012 Jan 29-31. Wengen, SwitzerlandYousafzai MS; Butt T; Oezalp F; Wrightson N; Nicola R; Pillay T; MacGowan G; Parry G; Siddique A; Schueler SVB. Improved Surgical Techniques of Left Ventricular Assist Device Drive Line Placement. International Society of Heart and Lung Transplantation Annual Meeting; 2012 Apr 18-21. Prague, Czech RepublicButt T; Siddique A; Yousafzai MS; Ozalp F; Roysam C; OLeary, D; Wrightson N; Schuster J; MacGowan G; Pillary T; Schueler SVB. Optimized RV Function Prior to LVAD Implantation-Honeymoon Period or Sustainable Success?. Society for Cardiothoracic Surgery Annual Meeting; 2012 Apr 18-20. Great Britain and Ireland, Manchester CentralTrujillo KP; Melin AA; Lackner R.; Siddique A. Extracorporeal Membranous Oxygenation Following Thoracic Surgery: A Single Center Experience. Southwestern Surgical Congress; 2015 April 26. Monterey CaliforniaRyan, Timothy; Siddique A; Burdorf, Adam; Merritt HM; Um; Moulton M. Cost Comparison of Extracorporeal Life Support on Survivors and Non. ISHLT; 2016 April. Washington, DCVarnado, Sarah; Siddique A; Burdoff, Adam; Merritt HM; Um J; Moulton M. Myocarditis Treated with VA-ECMO: A Single Centers Experience. ISHLT; 2016 April. Washington, DCRyan, Timothy; Siddique A; Burdoff, Adam; Um J; Merritt HM; Moulton M. Laboratory Variables Determining 30-Day Mortality in Veno-Arterial and Veno-Venous ECMO Patients. ISHLT; 2016 April. Washington, DCSiddique A; Um J; Merritt HM; Burdoff, Adam; Moulton M. Totally Percutaneous RVAD/ECMO Configuration Provides Versatile Support for RV Failure. ISHLT; 2016 April. Washington, DCRyan, TR; Burdorf, Adam; Lowes BD; Um JY; Siddique A; Merritt-Genore, HM; Varnado, SL. Financial Impact of Extracorporeal Life Support on Survivors versus Non-Survivors. 36th Annual International Heart and Lung Transplantation Scientific Sessions; 2016 April 27-30. Washington DCVarnodo S; Brink S; Balk J; Raichlin E; Lowes BD; Vongooru HR; Burdorf Adam; Um JY; Siddique A; Zolty R. CMV Reactivation Using Valganciclovir vs Valacyclovir in Moderate Risk Heart Transplant Recipients. 36th Annual International Heart and Lung Transplantation Scientific Sessions; 2016 April 27-30. Washington DCVarnado S; Burdorf AF; Higgins JV; Lowes BD; Zolty R; Vongooru H; Fenske BM; Siddique A; Moulton MJ; Um JY; Raichlin E. Cardiac allograft sinus tachycardia is associated with impaired exercise tolerance. 36th Annual International Heart and Lung Transplantation Scientific Sessions; 2016 April 27-30. Washington DCRhee, J; Bailey K; Siddique A. Who Will Survive Extracorporeal Membrane Oxygenation (ECMO). CHEST 2016 Annual Meeting; 2016 October. Los Angeles, CAZolty, R; Raichlin E; Burdorf, Adam; Vongooru HR; Ryan TR; Yannone SM; Ferguson K; Siddique A; Moulton MJ; Um JY; Lowes BD. Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with End-Stage Heart Failure and LVAD. American Heart Association Scientific Sessions 2016; 2016 November 12-16. New Orleans, LAMerritt; Um; Moulton M; Markin N; Siddique A. Tension Pneumopericardium in an LVAD, Rare but Real. ISHLT; 2017 April. San DiegoMerritt HM; Siddique A; Um J; Moulton M. The Effect of Recombinant-Activated Factor VII on Patients Requiring ECMO Support. ISHLT; 2017 April. San DiegoBerkheim D; Nicholas IV TA; Moulton M.; Strah, H.; Siddique A. Pain Pathway in Lung Transplantation is Associated with Excellent Peri-Operative Outcomes: A Case Series. International Society for Heart & Lung Transplantation; 2017 April 05. San DiegoRaichlin E; Selim AM; Zolty R; Burdorf AF; Siddique A; Moulton MJ; Um JY; Lowes BD. Cardiopulmonary Stress Test One Year after HTx Predicts the Development of CAV. 37th Annual International Heart and Lung Transplantation Scientific Sessions; 2017 April 5-8. San Diego, CASelim AM; Zolty R; Burdorf AF; Um JY; Siddique A; Moulton MJ; Lowes BD; Raichlin E. The Transmitral Peak Flow Velocity-Mitral Annular Diastolic Velocity Ratio (e/e') Does Not Predict Left Ventricular Filling Pressure Post Cardiac Transplant. 37th Annual International Heart and Lung Transplantation Scientific Sessions; 2017 April 5-8. San Diego, CASelim AM; Zolty R; Burdorf AF; Siddique A; Um JY; Moulton MJ; Lowes BD; Raichlin E. Higher Heart Rate is Associated with Lower Incidence of Coronary Allograft Vasculopathy Requiring Angioplasty. 37th Annual International Heart and Lung Transplantation Scientific Sessions; 2017 April 5-8. San Diego, CASelim AM; Raichlin E; Burdorf AF; um jy; Siddique A; Moulton MJ; Lowes BD; Zolty R. Left Ventricular Assist Devices Can Reverse Pulmonary Hypertension Group 2 with Significantly Elevated Pulmonary Vascular Resistance. American Thoracic Society (ATS) 17th International Conference; 2017 May 19-24. Washington DCJacob Moore; Kwapnoski ZJ; Moulton MJ; Siddique A; Um JY; Merritt-Genore HL. ECMO as a Bridge TO or FROM Cardiac Transplantation. ELSO Annual Meeting; 2017 September. Baltimore, MDKwapnoski ZJ; Moore, Jacob; Moulton MJ; Um JY; Siddique A; Merritt-Genore HL. The effect of hemoglobin on ECMO outcomes. CREF; 2017 September. San Diego, CAMerritt-Genore HL; Shoiab I; Smith SP; Siddique A; Um JY; Moulton MJ. Delayed Anticoagulation Initiation for ECMO Patients at High Risk of Exsanguination. Southern Thoracic Surgical Association; 2017 November. San Antonio, TexasKwapnoski ZJ; Siddique A; Um JY; Moulton MJ; Merritt-Genore HL. Nurse-Driven Protocol is Safe and Cost-Effective for ECMO Patients. Society of Thoracic Surgeons; 2018. Ft Lauderdale, FLLuksan AS; Berkheim D; Siddique A; Um JY; Moulton MJ; Merritt-Genore HL. Time is on Your Side: A Comparison of OR Times with ECMO Survival in Post Cardiotomy Patients. ISHLT; 2018 April. Nice, FranceSiddique A; Moulton MJ; Merritt-Genore HL; Strah HM. Aortic Stenosis and the Sensitized Lung Recipient- What would you do? 38th Annual International Heart and Lung Transplantation Scientific Sessions; 2018 April. Nice, FranceKL Bailey; TA Wyatt; HM Strah; DM Katafiasz; AJ Heires; A Siddique; TM Nordgren; DJ Romberger. Exosome inflammatory cytokine cargo from airway epithelial cells and mesenchymal stem cells in COPD patients and never smokers. American Thoracic Society (ATS) Annual International Conference. 2018 May. San Diego, CAAggarwal S, Pavlides G, O’Leary EL, Siddique A, Merritt-Genore H, Moulton MJ, Gumina RJ, Aronow HD, Goldsweig AM. Hemodynamics of Balloon-Expandable vs. Self-Expanding Transcatheter Aortic Valve. Transcatheter Valve Therapies (TVT) Summit. 2018 June. Chicago, ILUrban M; Siddique A; Um J; Merritt-Genore H, Moulton MJ. Outcome Analysis of Percutaneous VA ECMO as a Bridge to Durable LVAD. 29th Annual ELSO Conference. 2018 September. Scottsdale, AZ Asawaeer M, Pavlides G, Chatzizisis Y, O’Leary EL, Siddique A, Merritt-Genore H, Moulton MJ, Gumina R, Goldsweig AM. Patient Radiation Exposure Surrounding Transcatheter Aortic Valve Replacement. Transcatheter Cardiovascular Therapeutics (TCT) Annual Meeting. 2018 September. San Diego, CA.Schwabe M, Brady J, Al Emam A, Siddique A, Goldsweig AM. Periprocedural Anticoagulation Bridging with Fondaparinux for Mechanical Mitral Valve and Heparin Induced Thrombocytopenia. Transcatheter Cardiovascular Therapeutics (TCT) Annual Meeting. 2018 September. San Diego, CA.INVITED PRESENTATIONSSiddique A. ‘Contemporary Valve Clinic, Biologic, Mechanical, Autologous vs Homologous’. UNMC Cardiothoracic Surgery Grand Rounds; 2013 Dec 04. University of Nebraska Medical Center, Omaha, NESiddique A. ‘Lung Transplantation’. Nebraska Perfusion Society Annual Meeting; 2014 Feb 01. Omaha, NESiddique A. ‘Total Artificial Heart’. The Nebraska Assembly of the Association of Surgical Technologists Annual Winter Workshop; 2014 Mar 01. Omaha, NESiddique A. ‘ECMO- not your mother’s support any more’. Grand Rounds at the Department of Surgery. 2014 Sept 17. University of Nebraska Medical Center, Omaha, NESiddique A. ‘On pump vs off pump CABG’. Advances in Cardiovascular Medicine regional conference. 2015 January 31. Omaha, NESiddique A. ‘Lung Transplantation- the good, the bad… and the future’. Grands Rounds at the Department of Anesthesiology. 2016 March 21. University of Nebraska Medical Center, Omaha, NESiddique A. ‘Lung transplantation- surgical procedure and considerations’. Cardiology Nursing Fellowship: Heart/Lung Transplantation. 2016 June 29. Omaha, NESiddique A. ‘Lung Transplantation: making the transition from medical to surgical management of advanced lung disease’. The Seventh: Extraordinary Innovations and Emerging Trends in Transplantation and Oncology from Nebraska Medicine conference. 2016 July 26. Omaha, NESiddique A. ‘Lung transplantation- from 30’000 feet to the ‘nitty gritty’’. Grands Rounds at the Kansas City Pulmonary Round Table. 2017 January 09. Kansas City. MOSiddique A. ‘Lung transplantation- surgical procedure and considerations’. Cardiology Nursing Fellowship: Heart/Lung Transplantation. 2017 January 18. Omaha, NESiddique A. ‘Lung transplantation- surgical procedure and considerations’. Cardiology Nursing Fellowship: Heart/Lung Transplantation. 2017 June 16. Omaha, NESiddique A. ‘Lung transplantation: where are we now? what does the future hold?’. The Eighth: Extraordinary Innovations and Emerging Trends in Transplantation and Oncology from Nebraska Medicine conference. 2017 July 12. Omaha, NESiddique A. ‘Lung transplantation- surgical procedure and considerations’. Cardiology Nursing Fellowship: Heart/Lung Transplantation. 2018 January 18. Omaha, NESiddique A. ‘ECMO’. Nebraska Organ Recovery Services. 2018 January 29. Omaha, NESiddique A. ‘Blood conservation’. UNMC ECMO and Cardiopulmonary bypass course. 2018 March 02. University of Nebraska Medical Center, Omaha, NESiddique A. ‘The ins and outs of starting a lung transplant program’. The Ninth: Extraordinary Innovations and Emerging Trends in Transplantation and Oncology from Nebraska Medicine conference. 2018 July 24. Omaha, NESiddique A. ‘Lung transplantation: what’s new and what’s on the horizon’. Creighton Pulmonary Grand Rounds. 2018 September 17. Creighton University, Omaha, NESiddique A. ‘VA ECMO: first 24 hours and beyond, best strategies, limb issues’. ECLS Team Symposium: Advancing ECLS in Our Region and Beyond. 2018 October 26. University of Nebraska Medical Center, Omaha, NECOMMUNITY SERVICE/OUTREACHJune 2018 Outreach/education to Methodist Pulmonary Physicians, Omaha, NE for the lung transplant programAugust 2017Outreach/education to Great Plains Health, North Platte, NE for the cardiac surgery programJanuary 2017Educational community service with the Nebraska Big Red Alphas group (alpha-1 antitrypsin deficiency) to discuss lung transplantation November 2016Outreach/education to Nebraska Pulmonary Specialties, Lincoln, NE for the lung transplant programMay 2016Outreach/education to Methodist Physicians Clinic Heart Consultants, Omaha, NE for the cardiac surgery programSeptember 2015Outreach/education to Cardiovascular Associates in Sioux City, IA for the cardiac surgery program2012Volunteered in congenital cardiac surgery in Ethiopia for one month as part of a surgical missionPUBLICATIONS A. ARTICLES PUBLISHED IN SCHOLARLY JOURNALSHinnebusch BF, Ma Q, Henderson JW, Siddique A, Archer SY, Hodin RA. Enterocyte response to ischemia is dependent on differentiation state. J Gastrointest Surg. 2002;6:403-9.Hinnebusch BF, Henderson JW, Siddique A, Malo MS, Zhang W, Abedrapo MA, Hodin RA. Transcriptional activation of the enterocyte differentiation marker intestinal alkaline phosphatase is associated with changes in the acetylation state of histone H3 at a specific site within its promoter region in vitro. J Gastrointest Surg. 2003;7:237-44.Siddique A, Malo MS, Ocuin LM, Hinnebusch BF, Abedrapo MA, Henderson JW, Zhang W, Mozumder M, Yang VW, Hodin RA. Convergence of the thyroid hormone and gut-enriched Kruppel-like factor pathways in the context of enterocyte differentiation. J Gastrointest Surg. 2003;7:1053-61.Hinnebusch BF, Siddique A, Henderson JW, Malo MS, Zhang W, Athaide CP, Abedrapo MA, Chen X, Yang VW, Hodin RA. Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor. Am J Physiol Gastrointest Liver Physiol. 2004;286:G23-30.Malo MS, Zhang W, Alkhoury F, Pushpakaran P, Abedrapo MA, Mozumder M, Fleming E, Siddique A, Henderson JW, Hodin RA. Thyroid hormone positively regulates the enterocyte differentiation marker intestinal alkaline phosphatase gene via an atypical response element. Mol Endocrinol. 2004;18:1941-62.Grikscheit TC, Siddique A, Ochoa ER, Srinivasan A, Alsberg E, Hodin RA, Vacanti JP. Tissue-engineered small intestine improves recovery after massive small bowel resection. Ann Surg. 2004;240:748-54.Siddique A; Wrightson N; Macgowan GA; Schueler S. Device Thrombosis in the HeartWare left ventricular assist device. Ann Thorac Surg. 2013;95:1508.Sajjad M; Butt T; Oezalp F; Siddique A; Wrightson N; Crawford D; Pillary T; Schueler S. An alternative approach to explantation and exchange of the HeartWare left ventricular assist device. Eur J Cardiothorac Surg. 2013;43:1247-50.Siddique A; Bose AK; Ozalp F; Butt TA; Muse H; Morley KE; Dark JH; Parry G; Clark SC. Vascular anastomotic complications in lung transplantation: a single institution's experience. Interact Cardiovascular Thoracic Surgery. 2013;17:625-31.Oniscu GC,?Siddique A, Dark J. Dual temperature multi-organ recovery from a Maastricht category III donor after circulatory death. Am J Transplant. 2014;14:2181-6.?Raichlin E; Baibhav B; Lowes BD; Zolty R; Lyden ER; Vongooru HR; Siddique A; Moulton MJ; Um JY. Outcomes in Patients with Severe Preexisting Renal Dysfunction after Continuous-Flow Left Ventricular Assist Device Implementation. ASAIO J 2016;62:261-267.Merritt-Genore H, Siddique A, Um J, Moulton MJ, Markin NW. Rare but Real: Tension Pneumopericardium in a Patient with a Left Ventricular Assist Device. CASE (Phila). 2017;19:230-232.Baibhav B, Gedela M, Moulton M, Pavlides G, Pompili V, Rab T, Dangas G, Bhatt DL,?Siddique A, Chatzizisis YS. Role of Invasive Functional Assessment in Surgical Revascularization of Coronary Artery Disease. Circulation 2018;137:1731-1739.Article: Immunopathogenesis and Biomarkers of Recurrent Atrial Fibrillation Following Ablation Therapy in Patients with Preexisting Atrial Fibrillation Journal: Expert Review of Cardiovascular Therapy (IERK)Article ID: IERK 1562902Article: Immunopathogenesis and Biomarkers of Recurrent Atrial Fibrillation Following Ablation Therapy in Patients with Preexisting Atrial Fibrillation Journal: Expert Review of Cardiovascular Therapy (IERK)Article ID: IERK 1562902Contributed equally to this workB. ARTICLES ACCEPTED FOR PUBLICATION IN SCHOLARLY JOURNALS Agrawal DK, Siddique A. Rejuvenation of ‘broken heart’ with bioengineered gel. Journal of Thoracic and Cardiovascular Surgery C. ARTICLES SUBMITTED FOR PUBLICATION IN SCHOLARLY JOURNALS Urban M, Siddique A, Merritt-Genore H, Um J. What are the results of Venoarterial Extracorporeal Membrane Oxygenation Bridging to Heart Transplantation? Interactive Cardiovascular and Thoracic SurgeryD. BOOKS PUBLISHED, IN PREPARATION, SUBMITTED OR IN PRESS Not ApplicableE. CHAPTERS IN BOOKS Siddique A, S Schueler. Heart-Lung Transplantation. 2013. For 3rd edition of Duke Cameron, Current Therapy in Thoracic and Cardiovascular Surgery.F. BOOKS OR JOURNALS EDITED Not ApplicableG. ABSTRACTS AND PRELIMINARY COMMUNICATIONS Siddique A, Knoper SR, Raz Y, Coehlo-Anderson R, Wild J, Mineburg N, Daniel J, Moulton MJ. Recurrence of Bronchiolitis Obliterans May Limit Long-Term Outcomes in Lung Retransplantation. J Heart Lung Transplant 2011;30:S206–S207.Yousafzai SM, Butt T, Oezalp F, Wrightson N, Robinson-Smith N, Pillay T, McGowan G, Parry, G, Siddique A, Schueler S. Improved Surgical Technique of Left Ventricular Assist Device Drive Line Placement. J Heart Lung Transplant 2012; 31:S198–S199. Wrightson N, Schueler S, Butt T, Robinson-Smith N, Siddique A, Oezalp F, Pillay T, McGowan G. Driveline Exit Site in Long Term LVAD’s – Patient Choice or Surgeon’s Decision. J Heart Lung Transplant 2013;32:S80.Varnado S, Um JY, Vongooru H, Zolty R, Lowes BD, Huntsberry A, Burdorf A, Fenske B, Siddique A, Moulton MJ, Raichlin E. Cardiac Allograft Sinus Tachycardia Is Associated with Impaired Exercise Tolerance. J Heart Lung Transplant 2016;35:S299. Ryan TR, Burdorf A, Lowes BD, Um JY, Siddique A, Merritt-Genore HM, Varnado SL, Moulton MJ. Financial Impact of Extracorporeal Life Support on Survivors Versus Non-Survivors. J Heart Lung Transplant 2016;35:S269–S270.Varnado S, Um JY, Vongooru H, Zolty R, Lowes BD, Burdorf A, Fenske B, Huntsberry A, Siddique A, Moulton MJ, Raichlin E. Heart Rate and Cardiac Allograft Vasculopathy in Heart Transplant Recipients. J Heart Lung Transplant 2016;35:S197–S198.Varnado S, Brink H, Balk E, Raichlin E, Lowes BD, Vongooru H, Burdorf A, Um JY, Moulton MJ, Siddique A, Zolty R. CMV Reactivation Using Valganciclovir vs Valacyclovir in Moderate Risk Heart Transplant Recipients. J Heart Lung Transplant 2016;35:S284.Burdorf A, Varnado S, Balk JL, Ryan TR, Raichlin E, Vongooru H, Lowes BD, Zolty R, Um JY, Merritt-Genore HM, Moulton MJ, Siddique A. Myocarditis Treated with VA-ECMO: A Single Centers Experience. J Heart Lung Transplant 2016;35:S373–S374.Siddique A, Baus JE, Merritt-Genore HM, O’Leary EL, Ryan TR, McCain NT, Lyden ER, Um JY, Moulton MJ. Totally Percutaneous RVAD/ECMO Configuration Provides Versatile Support for RV Failure. J Heart Lung Transplant 2016;35:S163.Selim A, Zolty R, Burdorf A, Um JY, Siddique A, Moulton MJ, Lowes BD, Raichlin E. The Transmitral Peak Flow Velocity-Mitral Annular Diastolic Velocity Ratio (e/e') Does Not Predict Left Ventricular Filling Pressure Post Cardiac Transplant. J Heart Lung Transplant 2017;36:S392-393.Raichlin E, Selim A, Zolty R, Burdorf A, Siddique A, Moulton MJ, Um JY, Lowes BD. Cardiopulmonary Stress Test One Year After HTx Predicts the Development of CAV. J Heart Lung Transplant 2017;36:S296.Berkheim DB, Nicholas TA, Moulton MJ, Strah HM, Siddique A. Pain Pathway in Lung Transplantation Is Associated with Excellent Peri-Operative Outcomes: A Case Series. J Heart Lung Transplant 2017;36:S367.Merritt-Genore H, Smith S, Shoiab I, Siddique A, Lyden E, Ryan TR, Um JY, Burdorf A, Moulton MJ. The Effect of Recombinant-Activated Factor VII on Patients Requiring ECMO Support. J Heart Lung Transplant 2017;36:S247.Selim A, Zolty R, Burdorf A, Siddique A, Um JY, Moulton MJ, Lowes BD, Raichlin E. Higher Heart Rate Is Associated with Lower Incidence of Coronary Allograft Vasculopathy Requiring Angioplasty. J Heart Lung Transplant 2017;36:S293-294.Selim A, Raichlin E, Burdorf A, Um JY, Siddique A, Moulton MJ, Lowes BD, Zolty R. Left Ventricular Assist Device Improves Type II Pulmonary Hypertension with High Pulmonary Vascular Resistance. J Heart Lung Transplant 2017;36:S363.Luksan A, Berkheim DB, Ryan TR, Lyden E, Um JY, Siddique A, Moulton MJ, Merritt-Genore H. Time is on Your Side: A Comparison of OR Times with ECMO Survival in Post Cardiotomy Patients. J Heart Lung Transplant 2018;37:S471-472.H. PUBLISHED AUDIOVISUAL OR COMPUTER-BASED EDUCATIONAL MATERIALS AND COMPUTER SOFTWARE Not ApplicableI. PUBLISHED CONTINUING EDUCATION MATERIALS Not Applicable ................
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