I-SPOT Exclusion Medication List - NETT



I-SPOT Exclusion

Medication List

IA Fibrinolytics

• defibrotide

• streptokinase (Kabikinase, Streptase)

• tissue plasminogen activator t-PA:

o alteplase (Activase)

o reteplase (Retavase)

o tenecteplase (TNKase)

• urokinase (Abbokinase)

IV tPA is allowed in I-SPOT Protocol Version 2

Vitamin K Antagonists

• Acenocoumarol (Sintrom)

• Diphenadione

• Ethyl biscoumacetate (Tromexan)

• Phenindione

• Tioclomarol

• Warfarin (Coumadin/Jantoven)

Anticoagulants (IV or IA)

Heparin (IV or IA)

• Heparin Sodium

• Heparin/Dextrose

Note: DVT prophylaxis with subcutaneous heparin allowed

Low Molecular Weight Heparins (LMWH) at therapeutic or full dose for DVT/PE or other indications

• Bemiparin (Hibor/Ivor/Badyket)

• Certoparin (Embolex/Sandoparin)

• Dalteparin (Fragmin)

• Enoxaparin (Lovenox)

• Nadroparin (Fraxiparin)

• Tinzaparin (Innohep)

Note: DVT prophylaxis with subcutaneous LMWH allowed

Fondaparinux (Arixtra) at therapeutic or full dose

Note: DVT prophylaxis with fondaparinux allowed

Direct thrombin inhibitors

• Argatroban

• Bivalirudin (Angiomax)

• Dabigatran (Pradaxa)

• Desirudin (Iprivask)

• Hirudin

Factor Xa inhibitors

• Apixaban (Eliquis)

• Rivaroxaban (Xarelto)

GIIb-IIIa inhibitors

• abciximab (ReoPro)

• eptifibatide (Integrilin)

• tirofiban (Aggrastat)

**Remember: Antiplatelet Agents [clopidogrel (Plavix) and Aspirin] are allowed**

**Please call the hotline if you have questions about meds not on this list**

Hotline: 774-234-7768

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