Find your ED cure

Take the next steps

Visit your general practitioner or cardiologist to learn more about your risk for cardiovascular disease.

Visit to: ? Take the online ED quiz and get your

customized treatment results ? Find an ED specialist in your area ? Register for free educational seminars to

learn more about treatment options ?? Hear how real people like you have

found their ED cure ? Get common answers to common

questions about ED, penile implants and insurance coverage

Talk to someone who's been there. Email us at MHPatientEducation@ or call 1-844-4ED-CURE and we'll connect you with a patient who found a successful treatment for his ED.

Boston Scientific Corporation 300 Boston Scientific Way, Marlborough, MA 01752-1234 ? 2018 Boston Scientific Corporation or its affiliates. All rights reserved. MH-404216-AA DEC 2016

CONTENT IS PROVIDED BY BOSTON SCIENTIFIC. BOSTON SCIENTIFIC IS DEDICATED TO TRANSFORMING LIVES THROUGH INNOVATIVE MEDICAL SOLUTIONS THAT IMPROVE THE HEALTH OF PATIENTS AROUND THE WORLD.

Find your ED cure

End your frustration. Renew your confidence. Feel complete.

Erectile dysfunction and heart disease

Welcome

This brochure is designed to help you learn more about the connection between erectile dysfunction (ED) and cardiovascular disease -- and how you can find a solution to regain the confidence, control and wholeness you seek with an active, satisfying sex life.

The quotes featured throughout this brochure are from real men who have tried other treatment options for their ED and eventually received a penile implant. Their testimony is based on their own experience and may not be typical for all patients.

ED -- the inability to maintain an erection sufficient enough for sexual intercourse -- is a warning sign of heart problems. Cardiovascular disease (CVD) and ED share many of the same risk factors. If you're experiencing symptoms of ED, chances are you have or will develop coronary artery disease (CAD) or coronary vascular disease (CVD) and could be at risk for a heart attack or stroke. The severity of the ED directly correlates with the severity of heart disease in many patients.1,2

"I began experiencing ED in 1999. It was no doubt caused by my cardiovascular issues. I had a myocardial infarction in 2003, with eight stents implanted."

? Bill

"This is something very basic. It's part of a man's identity."

? David

ED & heart disease

Hardening of the arteries, caused by plaque buildup -- atherosclerosis -- limits blood flow to various parts of the body. Since the arteries supplying blood to the penis are much smaller than the ones supplying the heart, this problem may first show up as having difficulty achieving an erection.3

"With ED, you're just not quite measuring up from a masculine standpoint. It works

on you in very subtle ways."

? Dave

Erectile dysfunction usually occurs, on average, 3 years before the following:1,2 ? Coronary artery disease (CAD) ? Peripheral artery disease (PAD) ? Stroke ED can be a warning sign of a potential heart attack or cardiovascular event.1,2 Talk to your general practitioner or cardiologist about your risk for heart disease.

ED occurs before silent coronary disease in almost 70% of cases.4

Taking the next step

Once you've talked to your doctor about your risks for heart disease, there are many treatment options for you to explore to resolve your erectile dysfunction. Finding a satisfying treatment for ED can be a life-changing event for many men (and their partners) who may have struggled for years with a condition that can impact their self-esteem and affect their most intimate relationships.

"I had heart problems so I had the little nitro pills in my pocket. I couldn't take ViagraTM or any of those drugs because they can't be combined. So I went on to the next step."

? David

Find your best ED cure

If your doctor says your heart is healthy enough for sex, you may be ready to learn more about your options. Fortunately, there are many ways to treat ED today. Men taking nitrates for heart disease are generally not candidates for oral ED medications and those taking alpha-blocking agents for blood pressure may need to be closely monitored by their doctor.5 In addition, if blood flow to the penis is compromised due to atherosclerosis, or plaque buildup, medications may not be effective.

When ED medication is not the answer, there are other options.

"Dealing with ED really puts a huge emotional burden on you."

? Tom

"Why go the rest of your life without being able to have physical intimacy with your partner when there is a fix for it?"

? Bill

Know all your options

The important thing to know is that you are not alone -- there is hope for nearly every man suffering from ED. Treatment options include oral medications, vacuum devices, suppositories, injections and penile implants. These treatments work differently for different people, and some may be more effective than others for you.

An AMS 700TM Penile Implant is a unique solution because it allows you to be intimate wherever, whenever and for as long as you want. It lets you be spontaneous again, and it is reliable with no medication side effects or ongoing costs.

Cylinder inflated

Cylinder deflated in flaccid penis

Reservoir (shown inflated & deflated)

Momentary Squeeze (MS) PumpTM

Penile implants have been in clinical use for over 40 years6 and nearly 500,000 patients have been treated with a Boston Scientific penile implant.7

92% of patients and 96% of their partners reported sexual activity with the implant to be excellent or satisfactory.8

"In my case and I'm sure in other men's cases--it has brought us back to wholeness."

? David

Penile implants have helped hundreds of thousands of men return to an active, satisfying sex life.9

Could an AMS 700TM Penile Implant be right for you?

A penile implant is entirely contained within the body and is designed to be simple and easy to operate. It provides the ability to have an erection anytime you choose, and once activated, you can maintain an erection as long as you desire. It typically does not interfere with ejaculation or orgasm.8,10 The AMS 700 Implant is the only implant on the market clinically proven and supported by the FDA to reduce the risk of revision surgery due to infection.11

Caution: US Federal law restricts this device to sale by or on the order of a physician. Your doctor is your best source for information on the risks and benefits of the AMS 700TM with MS PumpTM Inflatable Penile Prosthesis. Talk to your doctor for a complete listing of risks, warnings and important safety information. The AMS 700TM with MS PumpTM Inflatable Penile Prosthesis is intended for use in the treatment of male erectile dysfunction (impotence). Implanting a penile prosthesis will damage or destroy any remaining ability to have a natural erection, as well as make other treatment options impossible. Men with diabetes, spinal cord injuries or skin infections may have an increased risk of infection. Implantation may result in penile shortening, curvature or scarring. Some AMS 700 devices contain an antibiotic (InhibiZoneTM Antibiotic Surface Treatment). The device may not be suited for patients who are allergic to the antibiotics contained within the device (rifampin, minocycline or other tetracyclines) or have systemic lupus. Potential risks may include: device malfunction/failure leading to additional surgery, device migration potentially leading to exposure through the tissue, wearing away/loss of tissue (device/tissue erosion) infection, unintended-inflation of the device and pain/soreness. MH-545411-AA

References

1. Vlachopoulous C, Jackson G, Stefanadis C, et al. Erectile dysfunction in the cardiovascular patient. Eur Heart J. 2013 Jul;34(27):2034-46. 2. Jackson G, Boon N, Eardley I, et al. Erectile dysfunction and coronary artery disease prediction: Evidence based guidance and consensus. Int J Clin Pract. 2010 Jun;64(7):848-57. 3. Montorsi P, Roumeguere T, Montorsi F, et al. Is there a link between erectile dysfunction and cardiovascular disease? EAU Update Series 2. 2004 Jun:2;43-8. 4. Gandaglia G, Briganti A, Jackson G, et al. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 May;65(5):968-78. 5. ViagraTM Prescribing Information, Pfizer Inc. Revised January 2010. 6. Scott FB, Bradley WE, Timm GW. Management of erectile impotence: use of implantable inflatable prosthesis. Urology. 1973 Jul:2(1):80-2. 7. Data on file with Boston Scientific. 8. Montorsi F, Rigatti P, Carmignani G, et al. AMS three-piece inflatable implants for erectile dysfunction: a longterm multi-institutional study in 200 consecutive patients. Eur Urol. 2000 Jan;37(1):50-5. 9. Penile prosthesis. European Society for Sexual Medicine (ESSM) Website: . society/esha/malesd/oraltreatments/penileprosthesis.html. Accessed January 1, 2013. 10. Penile Implants-Erectile Dysfunction. Sex Health Matters Website: http:// erectile-dysfunction/penile-implantserectile-dysfunction/P7. Accessed December 3, 2014. 11. FDA Approval Letter, N970012-S065.

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