CDC smallpox information

Serious uncommon autoimmun blistering disease. IgG produced aginst proteins in the skin and mucus membranes*** leading to acantholysis and intraepidermal bulla. H&P recurrent painful and oral mucosa. Flaccid blisters or bulla** residual erosions. Hyperpigmentaiton. Positive nikolsky's sign. Dx biopsy of tissue with immunofluoresncens ................
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