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The thickening of the skin is due both to inflammatory swelling as well as the mass of rapidly replicating keratinocytes; these “wildly” dividing cells of the stratum basal have been found to have cell cycle durations of only 36 hours compared to the normal 311 hours; in addition, the usual “turnover” time of 27 days to create a completely new layer of skin (beginning in the basal ... ................
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