REVISED SUPPLEMENTAL DIGITAL CONTENT 2
Inclusion criteria were: 1) existence of stables conditions allowing interruption of sedatives drugs for several hours with a fully awake patients defined as Glasgow coma scale above 13, 2) stable hemodynamic status defined as a mean arterial blood pressure > 65 mmHg without the use of vasoactive drugs for at least 24 hours 3) adequate gas ... ................
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