CPAP and sleep disorders - World Allergy
[Pages:136]Workshop
CPAP and sleep disorders
Fulvio Braido
Allergy and Respiratory Diseases Department University of Genoa
To explain better the pathophysiology of obstructive sleep apnea and its consequences
To emphasize the magnitude of the clinical problem
To make familiar the practical aspects of the treatment techniques
To identify unmet needs
Hystory of Sleep Breathing Disordes
Bickelmann AG, Burwell CS, Robin ED, Whaley RD.
Extreme obesity associated with alveolar hypoventilation. A pickwickian syndrome.
Am J Med 1956; 21: 811-8.
OSA Mile Stones
1956 ? Bickelmann AG, Burwell CS, Robin ED, Whaley RD. Extreme obesity associated with alveolar hypoventilation. A pickwickian syndrome. Am J Med 21: 8118.
1965 - Gastaut H, Tassinari CA, Duron B. Etude polygraphique des manifestations episodiques (hypniques et respiratoires) du syndrome de Pickwick. Rev Neural 112: 568-79.
1965 - Jung R, Kuhlo W. Neurophysiological studies of abnormal night sleep and the pickwickian syndrome. Prog Brain Res 18: 140-59.
1970 - Lugaresi E, Coccagna G, Mantovani M, Brignani F. Effets de la trach?otomie dans les hypersomnies avec respiration p?riodique. Rev Neurol 123: 267-8.
1972 - Lugaresi E. Organizer Symposium: Hypersomnia with Periodic Breathing. Rimini, Italy, May 25-27. Bull Physiopath Resp 8:967.
1981 - Sullivan CE, Issa FG, Berthon-Jones M, Eves L. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet i: 862-5.
OSA
It is caracterized by repetitive collapse of the upper airways during sleep
Hpopnea: reduction in the airflow > 30% SO2 decrease > 3% at least 10 second
Apnoea: reduction in the airflow > 90% for at least 90% of the event at least 10 second
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