CPAP and sleep disorders - World Allergy

[Pages:136]Workshop

CPAP and sleep disorders

Fulvio Braido

Allergy and Respiratory Diseases Department University of Genoa

To explain better the pathophysiology of obstructive sleep apnea and its consequences

To emphasize the magnitude of the clinical problem

To make familiar the practical aspects of the treatment techniques

To identify unmet needs

Hystory of Sleep Breathing Disordes

Bickelmann AG, Burwell CS, Robin ED, Whaley RD.

Extreme obesity associated with alveolar hypoventilation. A pickwickian syndrome.

Am J Med 1956; 21: 811-8.

OSA Mile Stones

1956 ? Bickelmann AG, Burwell CS, Robin ED, Whaley RD. Extreme obesity associated with alveolar hypoventilation. A pickwickian syndrome. Am J Med 21: 8118.

1965 - Gastaut H, Tassinari CA, Duron B. Etude polygraphique des manifestations episodiques (hypniques et respiratoires) du syndrome de Pickwick. Rev Neural 112: 568-79.

1965 - Jung R, Kuhlo W. Neurophysiological studies of abnormal night sleep and the pickwickian syndrome. Prog Brain Res 18: 140-59.

1970 - Lugaresi E, Coccagna G, Mantovani M, Brignani F. Effets de la trach?otomie dans les hypersomnies avec respiration p?riodique. Rev Neurol 123: 267-8.

1972 - Lugaresi E. Organizer Symposium: Hypersomnia with Periodic Breathing. Rimini, Italy, May 25-27. Bull Physiopath Resp 8:967.

1981 - Sullivan CE, Issa FG, Berthon-Jones M, Eves L. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet i: 862-5.

OSA

It is caracterized by repetitive collapse of the upper airways during sleep

Hpopnea: reduction in the airflow > 30% SO2 decrease > 3% at least 10 second

Apnoea: reduction in the airflow > 90% for at least 90% of the event at least 10 second

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