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|Drug |Reference and page number |Route of Administration |Main Clinical Use/Classification |Contraindications |
|(Generic or trade name) | | | |(Complications with disease or other drugs) |
|Acetaminophen |Plumb’s pg. 6 |Oral |-Antipyretic |- Do not use in cats or ferrets |
|-Tylenol | | |-Oral analgesic in dogs and small mammals |-Drug interactions with barbiturates, |
|-APAP | | |-May be beneficial in dogs with renal |doxorubicin, fenbendazole, isoniazid, |
|-Paracetamol | | |dysfunction for treatment of chronic pain |phenothiazines, propylene glycol, warfarin |
| | | |condition | |
|Acetazolamide |Plumb’s pg. 7-8 |IV or PO (with food) |-Carbonic Anhydrase Inhibitor Diuretic |-Contraindicated for patients with significant |
|-Diamox | | |-Aqueous humor production in the treatment of |hepatic, renal, pulmonary, or adrenocortical |
|-Dazamide | | |glaucoma, metabolic alkalosis, and for its |insufficiency, hyponatremia, hypokalemia, |
| | | |diuretic action. |hyperchloremic acidosis, or electrolyte |
| | | |-May be useful as an adjunctive treatment for |imbalance |
| | | |syringomyelia in dogs. | |
| | | |-In horses, adjunctive treatment for HYPP | |
|Acetylcysteine |Wanamaker/Massey |-Nebulization for pulmonary |-Mucolytic, Antidote |-Few side effects when nebulized, but can cause |
|-Mucomyst |Pg: 442 |use |-Break down thick respiratory mucus |nausea or vomiting when given orally |
| | |-Orally for acetaminophen |-Treat acetaminophen toxicity | |
| |Plumb’s pg. 11 |toxicity | | |
|Acetylsalicylic Acid |Wanamarker/Massey |IV or oral |-Analgesic, Antipyretic, Anti-inflammatory |Gastric irritation, which can lead to ulceration|
|-Aspirin |Pg. 302-303 | |-Relief from mild-moderate pain (arthritis/hip |and bleeding. Cats are highly susceptible to |
| | | |dysplasia) |overdose because they cannot metabolize it |
| |Plumb’s pg. 83 | |-Postadulticide treatment after HW disease |quickly. |
| | | |-Analgesic/antipyrexia | |
| | | |-Treatment for cats with cardiomyopathy | |
| | | |-Treatment for endotoxic shock | |
|Drug |Reference and page number |Route of Administration |Classification/Main Clinical Use |Contraindications (Complications with disease or |
|(Generic or trade name) | | | |other drugs) |
|Activated Charcoal |Wanamaker/Massey pg. 161, 448 |PO |-Oral adsorbent |-Not effective for mineral acids/alkalis |
|-Acta-Char | | |-Adsorbent used to treat poisoning |-Too rapid administration may induce |
|-Charcodote |Plumb’s pg. 202 | |-Control diarrhea |emesis/aspiration |
|-Toxiban | | | |-In small dogs/cats monitor for hypernatremia |
|Adaptil |Plumb’s pg. 852-853 |Diffusers, sprays |-Pheromone Behavior Modifier |-No significant adverse effects were located for |
| | | |-Useful in treating behaviors associated with |these products and are unlikely to occur |
| | | |fear or stress, or calming animals in new | |
| | | |environments or situations. | |
|Adequan |Wanamaker/Massey pg. 306-307, |IM, IA (horses), SC (small |-Proteolytic Enzyme Inhibitor, Chondroprotectant |-IA injections contraindicated if patient |
|-Polysulfated |472 |mammals) |-Reduces degenerative changes induced by |hypersensitive to PSGAG. |
|glycosaminoglycan | | |non-infectious or traumatic joint disease |-Should not be used in place of other treatments |
| |Plumb’s pg. 868 | |-Promotes activity in the synovial membrane |when infection is suspected or present or when |
| | | | |surgery or joint immobilization is required. |
|Afoxolaner |Plumb’s pg. 16 |PO |-Oral insecticide |-No labeled contraindications |
|-NexGard | | |-Treatment and prevention of flea infestations |-Safety in breeding, pregnant, or lactating dogs |
| | | |-Treatment and control of American dog tick |has not been evaluated. |
| | | | |-Use with caution in dogs with a history of |
| | | | |seizures and epilepsy |
|Albuterol |Plumb’s pg. 23 |PO, inhaled |-Beta-Adrenergic agonist |-Contraindicated in patients hypersensitive to |
|-Salbutamol | | |-Bronchodilator, alleviates bronchospasm or cough|the drug. |
|-Proventil | | | |-Should be used with caution in patients with |
|-Ventolin | | | |diabetes, hyperthyroidism, hypertension, seizure |
| | | | |disorders, or cardiac disease. |
| | | | |-Use in late stage pregnancy may inhibit uterine |
| | | | |contractions. |
|Allopurinol |Wanamaker/Massey pg. 123 |PO |-Xanthine Oxidase Inhibitor, Purine analog |-Should never be used in red-tailed hawks. |
|-Zyloprim | | |-Uric acid reducer in dogs, cats, reptiles, and |-Many potential drug interactions |
| |Plumb’s pg. 31 | |birds |(Aminophylline/theophylline, Amoxicillin or |
| | | | |Ampicillin, Azathioprine or Mercaptopurine, |
| | | | |Chlorpropamide, Cyclophosphamide, Cyclosprine, |
| | | | |Diuretics, Oral anticoagulants, |
| | | | |Trimethoprim/Sulfamethoxazole, Uricosuric agents,|
| | | | |urinary acidifiers) |
| | | | |-Use with caution in patients with renal or |
| | | | |hepatic dysfunction |
|Aluminum hydroxide gel |Plumb’s pg. 37 |PO, mixed with food |-Oral antacid/phosphate binder |-Chronic use may lead to electrolyte |
|-Amphogel | | |-Used to treat hyperphosphatemia in small animal |abnormalities, possible aluminum toxicity. |
| | | |patients and sometimes as a gastric antacid for |-Many potential drug interactions (Allopurinol, |
| | | |ulcers. |Chloroquine, Corticosteroids, Digoxin, |
| | | | |Ethambutol, Fluoroquinolones, Gabapentin, H-2 |
| | | | |Antagonists, Iron Salts, Isoniazid, |
| | | | |Penicillamine, Phenothiazines, Tetracyclines, |
| | | | |Thyroid hormones) |
|Altrenogest |Wanamaker/Massey pg. 178 |Oral |-Oral Progestin |-Minimal when altrenogest is used correctly. |
|-Regu-Mate | | |-Suppress estrus for synchronization (to suppress|-Can be absorbed through the skin and should be |
|-Matrix | | |estrus for long periods) |used with great caution by pregnant women or |
| | | |-Maintain pregnancy in mares with low levels of |anyone with vascular disorders |
| | | |progesterone | |
|Amikacin |Wanamaker/Massey pg. 233, 443 |SC, IM, IV, |-Aminoglycoside Antibiotic |-Ototoxic and Nephrotoxic |
|-Amiglyde-V (vet) | | |-Parental use only approved in dogs and is used |-Cats are very susceptible to vestibular effects |
|-Amikin (human) |Plumb’s pg. 40 | |to treat serious gram-negative infections |-Not approved for use in cattle or other food |
| | | |-Approved for intrauterine infusion in mares |animals |
| | | |-Intraarticular injection in foals to treat | |
| | | |septic arthritis | |
|Aminopentamide |Wanamaker/Massey pg. 443, |IM, SC, or Oral |-Anticholinergic, Antispasmodic |-Dose related |
|-Centrine |160-161 | |-Indicated in treatment of acute abdominal |-Contraindicated in glaucoma |
| | | |visceral spasm, pylorospasm, or hypertrophic |-Relatively contraindicated in tachycardia, heart|
| |Plumb’s pg. 45 | |gastritis and associated nausea, vomiting, and/or|disease, GI obstruction, paralytic ileus, severe |
| | | |diarrhea. For use in cats and dogs. |ulcerative colitis, obstructive uropathy, or |
| | | | |myasthenia gravis. |
|Aminophylline |Wanamaker/Massey pg. 108 |IV or IM |-Phosphodiesterase Inhibitor Bronchodilator |-Gastrointestinal upset, central nervous system |
|-Theophylline | | |-Bronchodilation in respiratory and cardiac |stimulation, tachycardia, ataxia, and arrhythmia |
|-Theo-Dur |Plumb’s pg. 46 | |conditions |-Precautions need to be taken in regards to other|
|-Slo-bid | | |-Mild heart stimulation |medications that the patient is taking, lots of |
| | | | |drug interactions. |
|Amitraz |Wanamaker/Massey pg. 292 |Topical |-Dermatological drug |-Transient sedation, lowered rectal temperature, |
|-Formamidine | | |-Primarily in the treatment of generalized |increased blood glucose level, seizures |
|-Mitaban |Plumb’s pg. 1218 | |demodicosis |-Read labels carefully |
|-Taktic | | | |- Do not stress animals out for 24 hours after |
|-Preventic Tick Collar | | | |application |
| | | | |-Wear gloves when applying and wash off any that |
| | | | |gets on human skin. |
|Amitriptyline |Wanamaker/Massey pg. 125 |PO |-Tricyclic Behavior Modifier, Antipruritic, |-Side effects such as dry mouth, rapid heart |
|-Elavil | | |Neuropathic Pain Modifier |rate, sedation |
| |Plumb’s pg. 50 | |-antidepressant and anxiolytic drug with |-High doses can cause heart toxicity |
| | | |anticholinergic |-Sometimes causes cats to be less interested in |
| | | |-antihistamine |grooming |
| | | |-anti-alpha-adrenergic |-Weight gain |
| | | |-anti-inflammatory |-May reduce seizure threshold in epileptic |
| | | |-analgesic |animals |
| | | |-symptomatic treatment of idiopathic FLUTD | |
|Amoxicillin trihydrate |Wanamaker/Massey pg. 443, 243 |PO, IM, SC |-Aminopenicillin |-Rarely occur |
|-Amoxi-Tabs | | |-Treats wide range of infections in various |-Allergic reactions may occur |
|-Amoxi-Drops |Plumb’s pg. 56-58 | |species |-May cause GI upset when given orally |
|-Amoxil | | |-Reasonable choice for treating abscesses in cats|-High or prolonged doses have been associated |
| | | |even before culture and susceptibility are |with neurotoxicity |
| | | |available |-Liver enzymes may rise |
|Aldosterone | |IV |-Mineralocorticoid hormone |-High levels can cause heart and blood vessel |
| | | |-Affects the body’s ability to regulate blood |damage |
| | | |pressure | |
| | | | | |
|Atipamezole |Plumb’s pg. 88 |IM, IV, IO |-Alpha-2 Adrenergic Antagonist |-No safety data on use in pregnant or lactating |
|-Antisedan | | |-Used as a reversal agent for Domitor |animals |
| | | | |-Adverse effects include vomiting, diarrhea, |
| | | | |hypersalivation, tremors, or excitation |
|Benazepril HCl |Wanamaker/Massey pg. 445, |PO |-Angiotensin Converting Enzyme (ACE) Inhibitor |-No recommended for acute kidney injury. |
|-Lotensin (human) |121-122 | |-Treat heart failure, hypertension, chronic renal|-Caution in patients with increased serum |
|-Fortekor (vet) | | |failure, protein-losing glomerulonephropathies in|creatinine, hyponatremia, coronary or |
| |Plumb’s pg. 107-108 | |dogs and cats |cerebrovascular insufficiency, SLE, hematologic |
| | | | |disorders |
| | | | |-Mildly fetotoxic at high doses |
| | | | |-GI upset is the most likely adverse effect, but |
| | | | |hypotension, renal dysfunction, and hyperkalemia |
| | | | |are possible |
|Bismuth subsalicylate |Wanamaker/Massey pg. 161 |PO |-Antidiarrheal, Gastroprotectant |-Very rare, limited to constipation |
|-BSS | | |-Control diarrhea and acts as an adsorbent |-Used with caution in cats because of the |
|-Pepto-Bismol |Plumb’s pg. 115 | | |conversion to aspirin |
| | | | |-Can result in black stools that resemble melena |
|Buprenorphine |Wanamaker/Massey pg. 87, 308 |IV, IM, SC |-Opiate Partial Agonist |-Respiratory depression, excitement |
|-Buprenex | | |-Potent analgesic that is used in several small |(cats/horses), nausea, vomiting, diarrhea, |
|-Simbadol |Plumb’s pg. 127-129 | |animal species with good results in cats |defecation, panting, convulsions |
| | | |-Mild to moderate pain relief in dogs, horses, |-Overdoses cause intense respiratory depression |
| | | |other small mammals | |
|Buspirone |Wanamaker/Massey pg. 94 |PO |-Anxiolytic |-Few serious side effects appear to exist |
|-Buspar | | |-Control of urine spraying/marking |-Not appropriate for acute treatment of |
| |Plumb’s pg. 131 | |-Control fearfulness and anxiety |situational anxieties |
| | | | |-Use with caution in patients with severe hepatic|
| | | | |or renal disease |
|Butorphanol |Wanamaker/Massey pg. 308 |SC, PO, IV, IM |-Opiate Partial Agonist |-Sedation, ataxia, anorexia, diarrhea |
|-Stadol | | |-Analgesic, premed, antitussive, antiemetic |-Contraindicated in patients with liver disease, |
|-Torbutrol |Plumb’s pg. 135-137 | | |hypothyroidism, or renal insufficiency, |
|-Torbugesic | | | |Addison’s, head trauma, increased CSF pressure, |
| | | | |in geriatric or severely debilitated patients. |
|Captopril |Wanamaker/Massey pg. 121-122 |PO |-Angiotensin-Converting Enzyme (ACE) Inhibitor |-Complications in patients with renal |
|-Capoten | | |-Treat heart failure, hypertension, chronic renal|insufficiency caused by excretion by the kidneys |
| |Plumb’s pg. 152-153 | |failure, and protein-losing | |
| | | |glomerulonephropathies in dogs and cats | |
|Carprofen |Wanamaker/Massey pg. 305 |PO, SC, IV, IM |-Non-steroidal anti-inflammatory agent |-Contraindicated in dogs with bleeding disorders,|
|-Rimadyl | | |-Relief of pain associated with degenerative |history of serious reactions to it or other |
|-Novox |Plumb’s pg. 161-162 | |joint disease and postoperative pain resulting |propionic-class NSAIDs |
|-Norocarp | | |from soft tissue or orthopedic repair |-Caution in geriatric patients or those with |
|-Quellin | | | |preexisting chronic disease |
| | | | |-Rarely may cause hepatic failure |
|Cefazolin sodium |Wanamaker/Massey pg. 238 |IV, IM |-1st Generation Cephalosporin |-Usually not serious and do not often happen |
|-Ancef | | |-No FDA approved products for veterinary use |-hypersensitivity, fever, eosinophilia, |
|-Kefzol |Plumb’s pg. 170-171 | |-Often used for surgical prophylaxis for |lymphadenopathy |
|-Zolicef | | |gram-positive coverage |-Pain at injection site |
| | | | |-May have potential for nephrotoxicity |
|Cefovecin |Wanamaker/Massey pg. 239 |SC |-Injectable Long-Acting Cephalosporin |-Well tolerated in dogs and cats. |
|-Convenia | | |-Treat skin infections in dogs |-Caution in concurrent use with NSAIDs, propofol,|
| |Plumb’s pg. 178-179 | |-Treat wounds and abscesses in cats |cardiac, anticonvulsant, and behavioral meds |
|Cefpodoxime proxetil |Wanamaker/Massey pg. 239-240 |PO |-3rd generation cephalosporin |-May cause diarrhea, vomiting, and allergic |
|-Simplicef (vet) | | |-Treatment of skin infections |reactions |
|-Vantin (human) |Plumb’s pg. 182-183 | | |-Contraindicated in hypersensitivity to it and |
| | | | |other cephalosporin drugs |
| | | | |-May need to adjust dose if patient has renal |
| | | | |disease |
|Ceftiofur |Plumb’s pg. 188-189 |IM, SC |-3rd generation Cephalosporin |- Potentially could cause hypersensitivity |
|-Excene | | |-Swine: treatment and control of swine bacterial |reactions, granulocytopenia, thrombocytopenia, or|
|-RTU | | |respiratory disease |diarrhea |
|-Spectramast | | |-Cattle: treatment of BRD, acute bovine |-Causes paint on IM injection |
| | | |interdigital necrobacillosis, acute metritis |-May need to reduce dose in renal failure |
| | | |-Intramammary, treatment for subclinical mastitis| |
|Cephalexin |Wanamaker/Massey pg. 241 |PO |-1st generation Cephalosporin |-Low occurrence of problems |
|-Keflex | | |-Treat dogs, cats, horses, rabbits, ferrets, and |-Salivation, tachypnea, excitability in dogs, |
|-Cefalexin |Plumb’s pg. 196-198 | |birds that are infected with Staphylococcus |emesis and fever in cats |
|-Rilexine | | | |-May need to reduce dose in patients with renal |
| | | | |failure. |
|Chlorambucil |Plumb’s pg. 204-205 |PO |-Immunosuppressant/ Antineoplastic |-Caution in patients with pre-existing bone |
|-Leukeran | | |-Neoplastic diseases, including lymphocytic |marrow depression, and infection |
| | | |leukemia, multiple myeloma, polycythemia vera, |-Potential teratogen |
| | | |macroglobulinemia, and ovarian adenocarcinoma. | |
|Chloramphenicol |Plumb’s pg. 206-207 |PO, IV, SC, IM |-Broad-Spectrum Antibacterial |-Banned in food animals. |
|-Chloromycetin | | |-Variety of infections in small animals and |-Extreme caution/avoidance in pre-existing |
| | | |horses, particularly those caused by anaerobic |hematologic disorders, pregnancy, neonates, |
| | | |bacteria |hepatic failure, and in cats; renal failure. |
| | | | |-May need to reduce dose in animals with hepatic |
| | | | |or renal insufficiency |
| | | | |-Potentially toxic to humans; have dosage-giver |
| | | | |avoid direct contact with medication |
|Chlorothiazide |Wanamaker/Massey pg. 119 |PO |-Thiazide diuretic |-Contraindicated in those with hypersensitivity |
|-Diuril | | |-Treatment of nephrogenic diabetes insipidus and |and pregnancy |
| |Plumb’s pg. 211-212 | |hypertension in dogs |-Extreme caution/avoidance in severe renal |
| | | | |disease, pre-existing electrolyte/water balance |
| | | | |abnormalities, impaired hepatic function, |
| | | | |hyperuricemia, SLE, diabetes mellitus |
| | | | |-Hyperkalemia |
| | | | |-Many drug interactions |
|Chlorpheneramine maleate |Wanamaker/Massey pg. 310 |PO |-Antihistamine |-Contraindicated in those with hypersensitivity |
|-Chlor-Trimeton | | |-Pruritus, urticaria/angioedema, laminitis, |-Caution in those with narrow angle glaucoma, |
| |Plumb’s pg. 213-214 | |Downer cow syndrome, motion sickness, reverse |hypertension, GI or urinary obstruction, |
| | | |sneezing syndrome, anaphylactic shock, UR tract |hyperthyroidism, cardiovascular disease |
| | | |conditions | |
|Chlorpromazine |Wanamaker/Massey pg. 155 |IM, IV, SC |-Phenothiazine Sedative/Antiemetic |-Contraindicated in horses |
|-Thorazine | | |-Used as an antiemetic in dogs and cats. |-Dosage may need to be reduced in |
| |Plumb’s pg. 215-216 | |-May be useful in treating cats with motion |debilitated/geriatric animals, those with hepatic|
| | | |sickness |or cardiac disease, or when combined with other |
| | | | |agents |
| | | | |-Use with caution in dehydrated animals |
| | | | |-Inject slowly IV, do not inject into arteries, |
| | | | |do not inject IM in rabbits |
| | | | |-May cause significant hypotension, cardiac rate |
| | | | |abnormalities, hypo- or hyperthermia, my cause |
| | | | |extrapyramidal effects at high doses in cats |
|Ciprofloxacin |Wanamaker/Massey pg. 251 |-Preferably PO on an empty |-Fluoroquinolone Antibiotic |-Contraindicated in food animals, history of |
|-Cipro | |stomach |-Activity against many gram-negative bacilli and |hypersensitivity to drug, in growing animals |
|-Cipro XR |Plumb’s pg. 224 | |cocci |because it may cause cartilage abnormalities |
| | | |May be used when a larger oral dosage of an IV |-Caution in hepatic or renal insufficiency, |
| | | |product is desired |dehydration |
| | | | |-Many potential drug interactions |
|Cisplatin |Plumb’s pg. 228-229 |IV |-Antineoplastic |-Contraindicated in cats, and patients with |
|-CDDP | | |-Useful in a variety of neoplastic diseases. |pre-existing significant renal impairment or |
|-Platinol-AQ | | | |myelosuppression |
| | | | |-Must be given slowly via IV, fast administration|
| | | | |can increase toxicity |
| | | | |-Teratogenic, fetotoxic |
| | | | |-Drug related deaths possible |
|Clavamox |Wanamaker/Massey pg. 243 |PO |-Potentiated Aminopenicillin |-Do not administer to rabbits, guinea pigs, |
|(Amoxicillin-clavulanic acid) | | |-Treatment of urinary tract, skin, and soft |chinchillas, hamsters or serious enteritis and |
|-Clavamox tablets (vet) |Plumb’s pg. 59-60 | |tissue infections in dogs and cats |clostridial enterotoxemia may occur |
|-Clavamox drops (vet) | | |-Treatment of canine periodontal disease, | |
|-Augmentin (human) | | |bacterial cystitis in female dogs, and | |
| | | |hepatobiliary infections in dogs or cats | |
|Clemastine |Wanamaker/Massey pg. 310 |PO |-Antihistamine |-use with caution in prostatic hypertrophy, |
|-Tavist | | |-Pruritus, urticaria/angioedema, laminitis, |bladder neck obstruction, severe cardiac failure,|
| |Plumb’s pg. 234-235 | |Downer cow syndrome, motion sickness, reverse |angle-closure glaucoma, or pyeloduodenal |
| | | |sneeze syndrome, anaphylactic shock, UR tract |obstruction |
| | | |conditions |-most likely side effects, dogs: paradoxical |
| | | | |hyperactivity, sedation, and cholinergic effects.|
| | | | |Cats: diarrhea |
|Clindamycin |Wanamaker/Massey pg. 250 |PO, IM, IV |-Lincosamide Antibiotic |-Contraindicated in horses, rodents, ruminants, |
|-Antirobe | | |-Commonly used to treat wounds, abscesses, and |lagomorphs |
|-Cleocin |Plumb’s pg. 237-239 | |osteomyelitis caused by Staphylococcus aureus in |-Use caution with liver or renal dysfunction, |
| | | |cats and dogs |consider reducing dosage if severe |
| | | |-Toxoplasmosis |-GI upset and esophageal strictures in cats when |
| | | | |given without food or a water bolus. |
| | | | |-Cats may have hypersalivation or lip smacking |
| | | | |after oral admin. |
| | | | |-IM injections cause pain at the injection site |
|Clomipramine |Plumb’s pg. 243-245 |PO |-Tricyclic Antidepressant |-Caution in seizure disorders, liver disease, |
|-Clomicalm | | |-Used in dogs and cats with obsessive compulsive |cardiac rate/rhythm disorders, urinary retention,|
|-Anafranil | | |disorders, but may be useful for other behavior |or reduced GI motility |
| | | |disorders |-May affected testicular size/function |
| | | |-Urine spraying |-Cats may be more sensitive than dogs |
| | | |-Feather picking in birds | |
|Corticotropin(ACTH) |Plumb’s pg. 260-261 |IM |-Hormonal Diagnostic Agent |-Adverse effects are unlikely unless using |
|-Acthar | | |-Stimulates cortisol release, used primarily to |chronically |
| | | |test for hyper- or hypoadrenocorticism |-Do not administer gel form IV |
| | | | |-Expensive |
|Cosequin |Plumb’s pg. 495-497 |PO |-Nutritional Supplement |-Not a regulated drug, choose products carefully |
|-Glucosamine/ Chondroitin | | |-Useful as an adjunctive treatment for |-Caution is advised in patients with |
|Sulfate | | |osteoarthritis or other painful conditions in |bronchoconstrictive conditions |
| | | |horses, cats, dogs; FLUTD in cats | |
|Cosyntropin |Plumb’s pg. 263 |IV |-Hormonal Diagnostic Agent |-Drug lab interactions |
|-Tetracosactide | | |-Primarily used as an alternative to ACTH to test| |
|-Cortrosyn | | |for adrenocortical insufficiency, or | |
| | | |hyperadrenocorticism. | |
|Cyanocobalamin |Wanamaker/Massey pg. 344 |IM, SC |-Vitamin/Nutritional |-Do not use in those hypersensitive to the drug, |
|(Vitamin B12) | | |-Management of B12 deficiencies |otherwise very safe. |
|-Vita-Jec Vitamin B12 |Plumb’s pg. 265-266 | | | |
|-Vitamin B12 injection | | | | |
|Cyclophospha-mide |Plumb’s pg. 266-268 |PO, IV |-Immunosuppressive/ Antineoplastic |-Contraindicated with prior anaphylaxis |
|-Cytoxan | | |-Used in small animals as both an antineoplastic |-Caution in patients with leukopenia, |
|-Neosar | | |agent and as an immunosuppressant. |thrombocytopenia, previous radiation therapy, |
| | | | |impaired hepatic or renal function, or in those |
| | | | |for whom immunosuppression may be dangerous |
| | | | |-Adequate monitoring essential |
|Cyclosporine |Wanamaker/Massey pg. 207 |Ophthalmic ointment/drops |-T-Cell Immunosuppressive Agent |-If therapy is stopped, clinical signs of KCS |
|-Optimmune | | |-Treatment of KCS (Keratoconjunctivitis sicca) |will often return |
|-Restasis (human) |Plumb’s pg. 1133 | |-Treatment of pannus |-Drug that is given for life to keep KCS symptoms|
| | | | |under control |
|Cystorelin |Saunders Handbook of Veterinary |IM, IV |-Hormone |-Use cautiously in animals with bone marrow |
|- Gonadorelin |Drugs: Small and Large Animals | |-Treatment of ovarian follicular cysts in dairy |suppression or renal disease |
| |pg. 363 | |cattle |-Use with penicillamine will increase risk of |
| | | | |hematologic adverse effects |
|Cyproheptadine |Wanamaker/Massey pg. 167 |PO |-Antihistamine |-Caution in urinary or GI obstruction, severe |
|-Periactin | | |-May be used in cats to block bronchoconstriction|CHF, narrow angle glaucoma |
| |Plumb’s pg. 273-274 | |and also as an appetite stimulant |-Cats may experience paradoxical |
| | | |-Antihistamine effects |hyperexcitability, some reports of hemolytic |
| | | |-Can be useful in management of |anemia in cats |
| | | |serotonin-syndrome in small animals | |
|Deracoxib |Plumb’s pg. 291-292 |PO |-Non-Steroidal Anti-inflammatory Agent |-Caution in patients with concurrent GI |
|-Deramaxx | | |-Treatment of post-operative pain and treatment |ulcerative diseases, renal, or hepatic |
| | | |of pain and inflammation associated with |dysfunction, those in hypopreoteinemic states, or|
| | | |osteoarthritis |with conditions that may predispose them to |
| | | |-May be useful alternative to piroxicam in |hypercoagulability |
| | | |adjunctive treatment of transitional cell |-Not approved or recommended for use in cats |
| | | |carcinoma of bladder | |
|Dormosedan |Plumb’s pg. 299-301 |OTM, IV, IM, SL |-Alpha-2 Adrenergic Agonist |-Contraindicated in those with heart block, |
|-Detomidine HCL | | |-Sedative analgesic used primarily in hoses |severe coronary, cerebrovascular, or respiratory |
| | | | |disease, chronic renal failure |
| | | | |-Caution in horses with endotoxic or traumatic |
| | | | |shock or approaching shock, advanced hepatic or |
| | | | |renal disease; stress due to temperature |
| | | | |extremes, fatigue, or high altitude, in patients |
| | | | |treated for intestinal impactions, with suspected|
| | | | |colic |
| | | | |-May respond to external stimuli even after fully|
| | | | |sedated |
| | | | |-Adverse: initial BP increase then |
| | | | |bradycardia/heart block |
|Desoxycortico-sterone pivalate|Plumb’s pg. 297-298 |IM, SC (extra label) |-Mineralocorticoid |-Contraindications: congestive heart failure, |
|-Percorten-V | | |-Used to treat Addison’s in dogs/cats |severe renal disease, or edema |
| | | | |-Caution in pregnancy |
|Dexamethasone |Plumb’s pg. 301-305 |IV, IM, PO |-Glucocorticoid |-Many potential drug and lab interactions |
|(Dexamethasone sodium | | |-Treatment of endocrine conditions, rheumatic |-Rabbits can develop serious adverse effects |
|phosphate) | | |diseases, collagen disease, allergic |-Patients need to be tapered off of this drug, do|
|-Azium | | |sates/anaphylaxis. |not stop cold turkey |
|-Dexasone | | | | |
|Dexmedetomidine |Plumb’s pg. 306-308 |IM |-Alpha-2 Adrenergic Agonist |-Contraindicated in cardiac disease, liver, or |
|-Dexdomitor | | |-Used as a preanesthetic and for sedation and |kidney diseases, shock, sever debilitation, or |
| | | |analgesia in dogs and cats |animals stressed out due to heat, cold, or |
| | | | |fatigue. |
| | | | |-Caution in very old or young animals, animals |
| | | | |with seizure disorders, respiratory, renal, or |
| | | | |kidney disorders |
| | | | |-Effects may be reversed with Atipamezole |
|Diazepam |Plumb’s pg. 312-314 |Rectal, intranasal, IV, PI, |-Benzodiazepine |-Contraindicated in hypersensitivity to |
|-Valium | |IM |-Anxiolytic, muscle relaxant, hypnotic, appetite |benzodiazepines, significant liver disease |
|-Diastat | | |stimulant, and anticonvulsant activities |(especially in cats), cats exposed to |
| | | |-Also used in preanesthetic protocols for |chlorpyrifos |
| | | |neuroleptanalgesia |-Caution in hepatic or renal disease, aggressive,|
| | | | |debilitated, or geriatric patients, patients in |
| | | | |coma or shock, or with significant respiratory |
| | | | |depression |
| | | | |-Inject IV slowly |
| | | | |-Many potential drug interactions |
|Dichlorophen |Plumb’s online |PO |-Carbonic Anhydrase Inhibitor |-Contraindicated in patients with significant |
|-Daranide | | |-Treatment of glaucoma |hepatic disease, renal or adrenocortical |
| | | | |insufficiency, hyponatremia, hypokalemia, |
| | | | |hyperchloremic acidosis, and electrolyte |
| | | | |imbalances |
| | | | |-Should not be used in patients with pulmonary |
| | | | |obstructions |
|Diethystilbestrol |Plumb’s pg. 323-325 |PO |-Hormonal agent |-Prohibited in food animals |
|-DES | | |-Used in dogs primarily for estrogen responsive |-Potential effects on bone marrow, should be used|
| | | |incontinence |with extreme caution in patients with |
| | | |-Has been used for the prevention of pregnancy |pre-existing anemias or leukopenias. |
| | | |after mismating in female dogs and cats |-Contraindicated in females with |
| | | | |estrogen-sensitive neoplasms |
|Digoxin |Plumb’s pg. 325-326 |PO, IV |-Cardiac Glycoside |-Contraindicated I those with V-fib, digitalis |
|-Lanoxin | | |-treatment of CHF, atrial fibrillation or |intoxication, cats with hypertrophic |
| | | |flutter, and supraventricular tachycardia |cardiomyopathy |
| | | | |-Extreme caution in patients with |
| | | | |glomerulonephritis and heart failure or with |
| | | | |idiopathic hypertrophic subaortic stenosis |
| | | | |-Drug interactions |
|Diltiazem |Plumb’s pg. 330-331 |PO, IV |-Calcium Channel Blocker |-Contraindications: severe hypotension, sick |
|-Cardizem | | |-Use for supraventricular tachycardia or |sinus syndrome or 2nd or 3rd degree AV block, |
|-Dilacor XR | | |decreasing the ventricular rate associated with |acute MI, radiographically documented pulmonary |
| | | |atrial fibrillation |congestion, hypersensitivity |
| | | | |-Caution in geriatric patients or those with |
| | | | |heart failure, or hepatic or renal impairment |
|Dioctyl calcium |Canine and Feline |PO, Rectally |-Emollient Laxative |-No studies done on efficacy in cats |
|Sulfosuccinate |Gastroenterology pg. 522 | |-Treatment of acute constipation |-Do not use for chronic constipation |
|-Docusate | | | | |
|Dobutamine |Plumb’s pg. 349-350 |CRI |-Parenteral Beta-Adrenergic Inotropic |-Contraindications: known hypersensitivity to the|
|-Dobutrex | | |-Short term treatment of heart failure |drug or to the preservative, patients with |
| | | |-Also useful in shock patients when fluid therapy|idiopathic hypertropic subaortic stenosis |
| | | |alone has not restored acceptable arterial blood |-caution in patients post myocardial infarction, |
| | | |pressure, cardiac output, and tissue perfusion |ventricular tachyarrhythmias or atrial |
| | | | |fibrillation |
|Dopamine |Plumb’s pg. 355-357 |CRI |-Adrenergic/ Dopaminergic Inotropic Agent |-Contraindicated in pheochromocytoma, ventricular|
|-Intropin | | |-Critical care settings only when adequate |fibrillation, and uncorrected tachyarrhythmia |
| | | |monitoring can be provided. | |
| | | |-Treatment of acute heart failure | |
|Doxorubicin |Plumb’s pg. 362-364 |IV |-Antineoplastic |-Contraindicated in patients with |
|-Doxil | | |-May be useful in treatment of a variety of |myelosuppression, impaired cardiac function, or |
|-Adriamycin | | |lymphomas, carcinomas , leukemias, and sarcomas |that have reach the total cumulative dose level |
| | | |in cats and dogs |-Monitor carefully in breeds predisposed to |
| | | | |developing DCM |
| | | | |-Handle very carefully, gloves should be worn |
| | | | |when administering or preparing |
| | | | |-Extreme caution must be taken to not go |
| | | | |perivascularly |
|Doxycycline |Plumb’s pg. 365-368 |PO, IV |-Tetracycline Antibiotic |-Drug interactions |
|-Vibramycin | | |-Used to treat a lot of small animals for a |-Esophagitis and strictures possible, must follow|
| | | |variety of infections like Borrelia, Leptospira, |oral doses with sufficient fluid to get |
| | | |Bartonella, and Bordetella |medication into stomach |
| | | |-Also is part of the recommended canine heartworm|-Do not use IV in horses, do not give IM or SC to|
| | | |treatment protocol |any species |
| | | | |-Should only be used in the last half of |
| | | | |pregnancy |
|Enalapril |Plumb’s pg. 374-376 |PO |-Angiotensin-Converting Enzyme Inhibitor |-Caution in pregnancy, renal insufficiency, |
|-Enacard | | |-Treatment of heart failure, proteinuria or |patients with hyponatremia, coronary or |
|-Vasotec | | |hypertension, may also benefit the treatment of |cerebrovascular insufficiency, pre-existing |
| | | |chronic renal failure |hematologic abnormalities or a collagen vascular |
| | | | |disease |
|Enrofloxacin |Plumb’s pg. 379-381 |PO, IM, SC, IV |-Fluoroquinolone Antibiotic |-Not for use in dairy cattle or veal calves |
|-Baytril | | |-Used in dogs and cats for treatment of bacteria |-Drug interactions |
| | | |susceptible to enrofloxacin (because of dosage |-Administer on empty stomach unless vomiting |
| | | |restrictions it is best to only use it in those |occurs |
| | | |most susceptible to Baytril) |-High doses not recommended for cats, it can |
| | | | |cause blindness |
| | | | |-Caution in hepatic or renal insufficiency or in |
| | | | |dehydration |
| | | | |-Contraindicated for young, growing animals due |
| | | | |to cartilage abnormalities |
|Ephedrine |Plumb’s pg. 383-384 |PO, IV, CRI |-Sympathomimetic Bronchodilator/ Vasopressor |-Contraindicated with severe cardiovascular |
| | | |-Treatment of urinary incontinence, has been used|disease, especially with arrhythmias |
| | | |in attempt to treat nasal congestion and |-Caution in patients with glaucoma, prostatic |
| | | |bronchoconstriction in small animals. |hypertrophy, hyperthyroidism, diabetes mellitus, |
| | | |-Can be used in the treatment of shock or |cardiovascular disorders, or hypertension |
| | | |anesthesia associated hypotension |-Excreted into milk, may affected neonates |
|Epinephrine |Plumb’s pg. 385-387 |IV, IO, IM, SC, IT |-Alpha- and Beta-Adrenergic Agonist |-Contraindications in narrow angle glaucoma, |
|-Adrenalin | | |-Treatment of anaphylaxis and cardiac restriction|hypersensitivity to epinephrine, shock due to |
| | | | |non-anaphylactoid causes, during general |
| | | | |anesthesia with halogenated hydrocarbons, during |
| | | | |labor, cardiac dilation or coronary |
| | | | |insufficiency, cases where vasopressor drugs are |
| | | | |contraindicated |
| | | | |-Do not inject with local anesthetics into small |
| | | | |appendages of the body, may cause |
| | | | |necrosis/sloughing |
| | | | |-Use with caution in patients with |
| | | | |prefibrillatory cardiac rhythm, and hypovolemia |
|Eprinomectin |Plumb’s pg. 392-393 |Topically, SC |-Topical Avermectin Antiparasitic Agent |-Pour-on as labeled = no withdrawal time |
|-Eprinex | | |-Gastrointestinal roundworms for cattle |-Injectable has a 48-day slaughter withdrawal and|
|-LongRange | | | |specific syringe compatibilities, must be |
| | | | |administered SC in front of shoulder |
| | | | |-Do not give orally or IV |
| | | | |-Under-dosing or sub-therapeutic concentrations |
| | | | |may encourage development of parasite resistance |
|Erythropoietin (Epoetin Alfa) |Plumb’s pg. 390-391 |SC, IM |-Erythropoietic Agent |-Contraindicated in patients with uncontrolled |
|-EPO | | |-Hormone that regulates erythropoiesis, used for |hypertension or in those that are hypersensitive |
|-rHuEPO | | |anemia associated with chronic renal failure |to the drug with formation of significant |
|-Epogen | | | |autoantibodies with prior treatment |
|-Procrit | | | |-Adequate monitoring is vital |
|Epsiprantel |Plumb’s pg. 394 |PO |-Cestocidal Antiparasitic Agent |-No FDA approved in puppies or kittens less than |
|-Cestex | | |-Treatment of tapeworms in dogs and cats |7 weeks old |
|Erythromycin |Plumb’s pg. 397-399 |PO |-Macrolide antibiotic |-Contraindicated in rabbits, gerbils, guinea |
|-Gallimycin | | |-Increase gastric emptying in dogs and cats |pigs, hamsters, do not us orally in ruminants, |
| | | |-Treatment of reflux esophagitis (mostly cats) |and possibly adult horses, or in those with |
| | | |and motility disorders in dogs (not cats) |hypersensitivity to the drug |
| | | | |-Many drug interactions |
|Estradiol cypionate |Plumb’s pg. 404-405 |IM |-Hormonal Agent (Estrogen) |-Contraindicated in pregnancy, and in food |
|-ECP | | |-Primarily used to induce estrace |animals (FDA has stated that it is illegal to use|
| | | | |ECP in food animals) |
|Etodolac |Plumb’s pg. 412-413 |PO, SC |-Non-Steroidal Anti-inflammatory Agent |-Contraindicated in those with hypersensitivity |
|-EtoGestic | | |-Management of pain and inflammation associated |to the drug |
|-Lodine | | |with osteoarthritis in dogs |-Caution in patients with pre-existing or occult |
| | | | |GI, hepatic, renal, cardiovascular or hematologic|
| | | | |abnormalities |
| | | | |-Safety not evaluated in dogs less than 12 months|
| | | | |of age or in breeding, lactating, or pregnant |
| | | | |dogs |
| | | | |-Keratoconjuctivitis sicca possible |
|Famotidine |Plumb’s pg. 418-419 |PO, IV |-H2 Receptor Antagonist |-Use cautiously in geriatric patients and |
|-Pepcid | | |-Treatment or prophylaxis of gastric, abomasal |patients with significantly impaired hepatic or |
| | | |and duodenal ulcers, uremic gastritis, |renal function. |
| | | |stress-related or drug related erosive gastritis,|-Too rapid IV infusion may cause bradycardia |
| | | |esophagitis, duodenal gastric reflux, and | |
| | | |esophageal reflux | |
|Feliway |Plumb’s pg. 852-853 |Diffuser/Spray |-Pheromone Behavior Modifier |-Do not spray directly on the cat |
|-Pheromones | | |-Useful for urine marking or spraying, vertical |-Very safe |
|-D.A.P. | | |scratching, avoidance of social contact, loss of | |
| | | |appetite, stressful situations, or inter-cat | |
| | | |aggression | |
|Fenbendazole |Plumb’s pg. 425-427 |PO, SC (Camelids) |-Antiparasitic Agent |-In dogs, give with food. |
|-Panacur | | |-Anthihelmintic for a variety of parasites in |-Antigen release by dying parasites may occur and|
|-Safe-Guard | | |dogs, cats, cattle, horses, swine, and other |cause vomiting |
| | | |animals. | |
|Fentanyl |Plumb’s pg. 436-437 |Topically (Transdermal) |-Opiate |-Adequate training for staff |
|-Recuvyra | | |-Control of post-operative pain associated with |-DVM Must report serious adverse effects to |
| | | |surgical procedures in dogs |manufacturer |
| | | | |-Only for use in dogs, safety in other animals |
| | | | |has not been researched |
| | | | |-Safety has not been studied in those with |
| | | | |respiratory disease, dogs younger than 6 months |
| | | | |old, geriatric dogs, breeding, pregnant, or |
| | | | |lactating dogs. |
| | | | |-Do not apply to skin that is diseased or injured|
| | | | |-Must be recorded on RiskMAP |
|Firocoxib |Plumb’s pg. 444-446 |PO, IV |-COX-2 Inhibitor (NSAID) |-Use with caution in patients with pre-existing |
|-Previvox | | |-Control of pain and inflammation associated with|renal, hepatic, or cardiovascular dysfunction, |
|-Equioxx | | |osteoarthritis in dogs and horses |and those that are dehydrated, hypovolemic, |
| | | | |hypotensive, or on diuretic therapy. |
| | | | |-Many potential drug interactions |
|Fluazuron/ |Plumb’s pg. 586-588 |PO, SC, IM |-Antiparasitic |-Contraindicated in foals less than 4 months of |
|Ivermectin | | |-Used in a variety of species as an |age, and in puppies less than 6 months. |
|-Heartgard | | |anti-parasiticide |-Caution in breeds that are susceptible to |
|-Ivomec | | | |neurologic toxicity (Collie-type breeds) |
| | | | |-Not approved in lactating dairy animals or |
| | | | |females of breeding age |
| | | | |-Injectable products for cattle and swine should |
| | | | |be given SC, DO NOT give IV or IM |
| | | | |-Many possible drug interactions |
|Fluconazole |Plumb’s pg. 449-451 |PO, IV |-Antifungal |-Caution in animals with renal failure and |
|-Diflucan | | |-Treatment of systemic mycoses |pregnancy |
| | | | |-Many possible drug interactions |
|Flunixin meglumine |Plumb’s pg. 458-460 |IV, IM, SC, PO |-Non-Steroidal Anti-inflammatory Agent |-Use with caution in patients with renal, |
|-Banamine | | |-Horses: alleviation of inflammation and pain |hepatic, or hematologic diseases |
| | | |associated with musculoskeletal disorders and |-In horses with known or suspected EGUS, use |
| | | |alleviated of visceral pain associated with |should be avoided |
| | | |colic. |-IM route in cattle is extra-label and should not|
| | | |-Cattle: control of pyrexia associated with |be used if an IV route is available |
| | | |bovine respiratory disease and endotoxemia, and |-Contraindicated in cats |
| | | |control of inflammation in endotoexemia. |-Use in birds is generally avoided |
| | | |-Swine: control pyrexia associated with swine | |
| | | |respiratory disease. | |
| | | |-Ruminants: Visceral pain more so than | |
| | | |musculoskeletal pain. | |
| | | |-Has also been suggested for many other | |
| | | |indications in various species | |
| | | |Horses: foal diarrhea, shock, colitis, | |
| | | |respiratory disease, post-race treatment, and | |
| | | |pre- and post-ophthalmic and general surgery | |
| | | |Dogs: disk problems, arthritis, heat stroke, | |
| | | |diarrhea, shock, ophthalmic inflammatory | |
| | | |conditions, pre- and post-ophthalmic and general | |
| | | |surgery, and treatment of parvovirus infection | |
| | | |Cattle: acute respiratory disease, acute coliform| |
| | | |mastitis with endotoxic shock, pain, and calf | |
| | | |diarrheas | |
| | | |Swine: agalactia/hypolactia, lameness, and piglet| |
| | | |diarrhea | |
|5-Fluorouracil |Plumb’s pg. 461-462 |IV, intratumoral |-Antineoplastic agent |-Contraindicated in cats in any more. Patients |
|-Adrucil | | |-Canine mammary carcinoma, dermal squamous cell |with hypersensitivity to the drug, those in poor |
| | | |carcinoma, and GI tract tumors |nutritional states, depressed bone marrow, and |
| | | |-Topically and intralesional injections with |those with serious iinfection |
| | | |epinephrine into certain skin neoplasms in horses| |
|Fluoxetine |Plumb’s pg. 462-464 |PO |-Selective Serotonin-Reuptake Inhibitor (SSRI) |-Contraindicated in those with a hypersensitivity|
|-Prozac | | |-Helpful in treatment of canine aggression, |to the drug, or those receiving monoamine oxidase|
|-Reconcile | | |stereotypic behaviors, anxiety, and other |inhibitors |
| | | |obsessive compulsive behaviors |-Caution in patients with diabetes mellitus or |
| | | |May be useful in cats with inappropriate |seizure disorders, dosages may need to be reduced|
| | | |elimination |in patients with severe hepatic impairment |
| | | |-Should be used with a behavior modification plan|-Many drug interactions |
|Furosemide |Plumb’s pg. 475-477 |IV, IM, PO, SC |-Loop Diuretic |-Contraindicated in patients with anuria, |
|-Lasix | | |-Congestive cardiomyopathy, pulmonary edema, |hypersensitivity or seriously depleted |
|-Frusomide | | |hypercalcuric nephropathy, uremia, adjunctive |electrolytes |
| | | |therapy in hyperkalemia, and occasionally has a |-Caution in patients with pre-existing |
| | | |hypertensive agent. |electrolyte or water balance abnormalities, |
| | | | |impaired hepatic function, and diabetes mellitus |
|Gabapentin |Plumb’s pg. 478-480 |PO |-Anticonvulsant: Neuropathic Pain Analgesic |-Caution in patients with diminished renal |
|-Neurontin | | |-Useful in dogs and cats as adjunctive therapy |function, dogs partially metabolize the drug |
| | | |for refractory or complex partial seizures and in|-Avoid using xylitol-containing oral liquid in |
| | | |many species for the treatment of pain |dogs |
| | | |(especially neuropathic pain) |-Patients must be weaned off the medication, do |
| | | | |not stop abruptly |
|Gamithramycin |Plumb’s pg. 481-482 |SC |-Macrolide (Azalide) Antibiotic |-35-day slaughter withdrawal time |
|-Zactran | | |-Treatment of bovine respiratory disease in beef |-Contraindicated in animals that are |
| | | |and non-lactating dairy cattle. |hypersensitive to it |
| | | |-Potentially useful in horses, especially foals | |
|Gentamicin |Plumb’s pg. 485-487 |IV, IM, SC |-Aminoglycoside Antibiotic |-Cats may be more sensitive to toxic effects, |
|-Gentocin | | |-Active against a variety of bacteria, |especially vestibular |
|-Garamycin | | |predominantly gram-negative aerobic bacilli, but |-Use with extreme caution in patients with |
| | | |also many staphylococci strains |pre-existing renal disease |
| | | | |-Because the effects of aminoglycosides can cause|
| | | | |irreversible ototoxicity, they should be used |
| | | | |with caution in “working” or service dogs |
| | | | |-Contraindicated in rabbits |
|Gentamicin/ |Wanamaker/Massey pg. 219 |Otic |-Antibiotic, Antipruritic, Anti-inflammatory |-Do not use in pregnant animals |
|Mometasone/ | | |-Useful in treatment of itching and inflamed skin|-May delay healing when used for more than 7 days|
|Clotrimazole | | |that may be associated with bacterial or yeast | |
|-Mometamax | | |infections | |
|-Otomax | | | | |
|Glipizide |Plumb’s pg. 490-491 |PO |-Sulfonylurea Antidiabetic Agent |-Contraindicated in those with severe burns, |
|-Glucotrol | | |-Benefit in treating cats with type 2 diabetes if|trauma, infection, diabetic coma, or other |
| | | |they have a population of functioning beta cells |hypoglycemic conditions, major surgery, ketosis, |
| | | | |ketoacidosis or other acidotic conditions |
| | | | |-Caution in untreated adrenal or pituitary |
| | | | |insufficiency, thyroid, renal or hepatic function|
| | | | |impairment, prolonged vomiting, high fever, |
| | | | |malnourishment, or debilitated condition |
| | | | |-Many drug interactions |
|Glucosamine chondroitin |Plumb’s pg. 495-496 |PO |-Nutritional Supplement |-Not a regulated drug |
|sulfate | | |-Useful as an adjunctive treatment for |-Caution is advised in those with |
|-Cosequin | | |osteoarthritis or other painful conditions in |bronchoconstrictive conditions |
| | | |horses, cats, dogs | |
| | | |-FLUTD in cats | |
|Glycopyrrolate |Plumb’s pg. 500-502 |IV, IM, SC |-Anticholinergic (Antimuscarinic) |-Contraindicated in conditions where |
|-Robinul | | |-Preanesthetic |anticholinergic effects would be detrimental, not|
| | | |-Extra-label use to treat sinus bradycardia, |recommended for treating bradycardia secondary to|
| | | |sinoatrial arrest, and incomplete AV block |dexmedetomidine |
| | | | |-Many potential drug interactions |
|Griseofulvin |Plumb’s pg. 506-507 |PO |-Antifungal Agent |-Contraindicated in pregnancy, known |
|-Fulvicin | | |-Used primarily for ringworm and other |hypersensitivities, or hepatocellular failure. |
| | | |dermatophytic infections, no effected on other |Known teratogen in cats. |
| | | |fungi. |-Caution in kittens, they may be overly sensitive|
| | | | |to the drug, and in cats with FIV |
|Hemoglobin glutamer |Plumb’s pg. 510-511 |IV |-Semi-Synthetic Hemoglobin Replacer, Colloid |-Contraindicated in advanced cardiac disease, |
|-HG-200 | | |-treatment of anemia |real impairment with oliguria or anuria |
|-Hb-200 | | | |-Potential drug-lab interactions |
|-HBOC-301 | | | | |
|-Oxyglobin | | | | |
|Hetastarch |Plumb’s online |IV |-Colloid Volume Expander |-Contraindicated in those with fluid overload, |
|-Hydroxyethyl Starch Colloids | | |-Increase blood pressure and support colloid |and especially in cases where pulmonary edema is |
|(HES) | | |osmotic pressure |present, or in those with congestive heart |
| | | | |failure |
| | | | |-Do not use in those with intracranial bleeding |
|Hydralazine |Plumb’s pg. 516-517 |PO, SC, IV, CRI |-Vasodilator |-Contraindicated with known hypersensitivity, |
|-Apresoline | | |-Hypertension or adjunctive treatment for heart |coronary artery disease, hypovolemia, or |
| | | |failure |pre-existing hypertension |
| | | | |-Caution with severe renal disease, intracerebral|
| | | | |bleeding, pre-existing autoimmune disease |
| | | | |-Many potential drug interactions |
|Hydrocortisone |Plumb’s pg. 522-524 |IV as CRI, PO |-Glucocorticoid |-Many drug interactions |
|-Cortef | | |-Most commonly used when glucocorticoid and |-Contraindicated in systemic fungal infections |
|-Solu-Cortef | | |mineralocorticoid activity is desired (Addisonian|-Patients should be tapered off when given |
| | | |crisis, CIRCI) |chronically |
|Hydroxyzine |Plumb’s pg. 534-535 |PO |-Antihistamine |-Caution in those with prostatic hypertrophy, |
|-Atarax | | |-Antihistamine, antipruritic, and |bladder neck obstruction, severe cardiac failure,|
|-Vistaril | | |sedation/tranquilization effects. |angel-closure glaucoma, or pyeloduodenal |
| | | | |obstruction |
|Ibuprofen |Plumb’s pg. 1242 |PO |-NSAID |-Toxic to dogs, cats, and ferrets, not |
|-Advil | | |-TOXIC, DO NOT USE IN DOGS AND CATS |recommended for veterinary use. |
|-Motrin | | | |-Gastrointestinal ulceration may occur |
|Imidacloprid/ |Plumb’s pg. 1223 |Topical (collar) |-Dermatologic |-Watch weight and age limits as listed on the |
|Flumethrin | | |-Treatment of adult and larval stage of fleas in |package |
|-Seresto | | |dogs and cats |-Consult DMV before using on aged, debilitated, |
| | | | |pregnant, nursing, or medicated animals |
|Imipramine |Plumb’s pg. 548-549 |PO, IV |-Tricyclic Antidepressant |-May reduce seizure thresholds in epileptic |
|-Tofranil | | |-Used primarily in dogs and cats for urinary |animals |
| | | |incontinence, cataplexy, and tricyclic-responsive|-Can be very toxic in overdoses |
| | | |behavior disorders. |-May be teratogenic |
| | | |-In horses, treats narcolepsy and ejaculatory | |
| | | |dysfunction | |
|Indoxacarb |Merck Online |Topical |-Dermatological |-Read labels for warnings on weight and ages |
|-Actyvil |Plumb’s Online | |-Treatment of fleas |limits on species. |
|Insulin,regular |Plumb’s Online |SC |-Hormone |-No contraindications except when dealing with |
|-Humulin R | | |-Treatment of diabetic ketoacidosis, |hypoglycemia |
| | | |uncomplicated diabetes mellitus, and as |-Drug interactions |
| | | |adjunctive therapy in treating hyperkalemia |-Pay close attention to syringes |
|Insulin, NPH, Ultralente, or |Plumb’s Online |SC |-Hormone, immediate acting insulin |-No contraindication except with hypoglycemia |
|PZI | | |-Treatment of diabetic ketoacidosis, |-Drug interactions |
| | | |uncomplicated diabetes mellitus, and as |-Pay close attention to syringes |
| | | |adjunctive therapy in treating hyperkalemia | |
|Interferon |Plumb’s pg. 558-559 |SC, PO |-Immunomodulator |-Low dose oral therapy is contraindicated in cats|
|-huIFN-alfa | | |-Primarily used to treat a variety of |with FIP |
|-Intron-A | | |virus-induced disease in cats |-Consider the risks vs the benefits in patients |
| | | |-In dogs it has been used for the adjunctive |with pre-existing autoimmune disease, severe |
| | | |treatment of viral or immunosuppression related |cardiac disease, pulmonary disease, brittle |
| | | |conditons. |diabetes, herpes infections, hypersensitivity to |
| | | | |the drug, and CNS disorder |
|Ipecac syrup | |PO |-Emetic |-Do not use when chemicals or items that can |
| | | |-Induction of vomiting when poisonous material |cause burns, or cuts are ingested |
| | | |ingested | |
|Iron |Plumb’s pg. 570-571 |IM, PO |-Injectable Hematinic |-Do not give IV or SC |
| | | |-Treatment and prophylaxis of iron deficiency |-Contraindicated in those with known |
| | | |anemias, primarily in neonatal food-producing |hypersensitivity to iron dextran, or with any |
| | | |animals |anemia than iron deficiency anemia. Those with |
| | | |Commonly given when dogs and cats receive |acute renal infections, in conjunction with oral |
| | | |erythrocyte stimulating agents |iron supplements |
| | | | |-IM use in pigs after 4 weeks of age may cause |
| | | | |muscle tissue staining |
|Isoflurane |Plumb’s pg. 573-575 |Inhalant |-General anesthetic, inhalant |-Contraindicated in those with history or |
|-Isoflo | | |-Primary inhalant anesthetic |predilection towards malignant hyperthermia |
|-Iso-Thesia | | | |-Caution with increased CSF or head injury, or |
| | | | |myasthenia graivs |
| | | | |-May be fetotoxic |
| | | | |-Drug interactions |
|Isoproterenol |Plumb’s pg. 577-578 |IV infusion, CRI |-Beta-Adrenergic Agonist |-Contraindicated with tachycardia or AV block |
|-Isoprenoline | | |-Infrequently used in vet med in the treatment of|caused by cardiac glycoside intoxication, |
|-Isuprel | | |acute bronchial constriction, cardiac |ventricular arrhythmias that do not require |
| | | |arrhythmias, and occasionally as adjunctive |increased inotropic activity |
| | | |therapy in shock or heart failure |-Caution in coronary insufficiency, |
| | | | |hyperthyroidism, renal disease, hypertension, or |
| | | | |diabetes. |
| | | | |-Not a substitute for adequate fluid replacement |
| | | | |in shock |
|Itraconazole |Plumb’s pg. 583-585 |PO |-Antifungal |-Contraindicated in those with hypersensitivity |
|-Sporanox | | |-Used for systemic and cutaneous mycoses |to it or other –azole antifungal agents, hepatic |
|-Intrafungol | | | |impairment, or achlorhydria (or hypochlorhydria) |
| | | | |-Drug interactions |
| | | | |-Use with caution in animals with reduced cardiac|
| | | | |function as itraconazole may have a negative |
| | | | |inotropic effect |
|Ivermectin |Plumb’s 586-590 |PO, SC, IM |-Antiparasitic |-Contraindicated in animals younger than listed |
|-Heartgard | | |-Used in a variety of species as an |on package instructions and lactating dairy |
|-Ivomec | | |antiparasiticide |animals |
| | | | |-Use caution in collie like breeds |
|Kaopectate |Plumb’s pg. 591-592 |PO |-GI Adsorbent/Protectant |-Contraindications: should not be relied on to |
|-Kaolin | | |-Treatment of diarrhea and GI toxins |control severe diarrhea or replace adequate |
|-Pectin | | | |fluid/electrolyte monitoring, or as replacement |
|-Kaopectolin | | | |therapy in severe or chronic diarrhea |
| | | | |-Transient constipation |
| | | | |-Drug interactions |
|Ketamine HCl |Plumb’s pg. 592-598 |IM, IV, CRI, IP |-Dissociative General Anesthetic; NMDA-Receptor |-Contraindicated in those with prior |
|-Ketaset | | |Antagonist |hypersensitivity, animals to be used for human |
|-Ketaflo | | |-Restraint or as the sole anesthetic agent for |consumption, alone for general anesthesia, |
|-Vetalar | | |diagnostic, or minor, brief, surgical procedures |increased CSF pressure/head trauma. |
| | | |that do not require skeletal muscle relaxation |-Relative contraindications: Significant blood |
| | | | |loss, malignant hyperthermia, increased |
| | | | |intra-ocular pressure or open globe injuries, |
| | | | |procedures involving the pharynx, larynx, or |
| | | | |trachea. |
| | | | |-Caution in those with significant hypertension, |
| | | | |heart failure, and arterial aneurysms, hepatic or|
| | | | |renal insufficiency, or seizure disorders |
| | | | |-Must use eye lubricant |
| | | | |-Minimize handling or loud noises during recovery|
| | | | |period, but monitor adequately |
|Ketoconazole |Plumb’s pg. 599-602 |PO |-Azole antifungal |-Contraindications: known hypersensitivity, some |
|-Nizoral | | |-Treat several types of fungal infections in |believe it is contraindicated in cats |
| | | |dogs, cats, and other small species |-Caution in hepatic disease or thrombocytopenia |
| | | |-Has been used to treat hyperadrenocorticism in |-Potentially teratogenic and embryotoxic |
| | | |dogs |-May cause infertility in male dogs by decreasing|
| | | | |testosterone synthesis |
| | | | |-Many drug interactions |
|Ketoprofen |Plumb’s pg. 603-605 |IV, IM, SC |-Non-steroidal anti-inflammatory agent |-Cautions: GI ulcers or bleeding, |
|-Ketofen | | |-Used to alleviate inflammation and pain |hypoproteinemia, breeding animals, significant |
|-Anafen | | |associated with musculoskeletal disorders, |renal or hepatic impairment |
| | | |lameness and pain due to osteoarthritis, hip |-Do not administer intra-arterially and avoid SC |
| | | |dysplasia, disc disease, spondylosis, |injections |
| | | |panosteitis, trauma, and related musculoskeletal |-Drug to drug interactions and drug-lab |
| | | |disease. Also for the management of post-surgical|interactions |
| | | |pain |-Do not use in animals intended for human |
| | | | |consumption |
|Lactated Ringer’s solution |Wanamaker/Massey pg. 336 |IV, SC |-Irrigation solution, |-Use caution not to overhydrate |
|-LRS | | |-Rehydrate, maintain hydration, replacement of |-Rotate sites with SC |
|-Normosol R | | |fluids | |
|Lactulose |Plumb’s pg. 608-609 |PO, Enema |-Disaccharide Laxative/ Ammonia Reducer |-May alter insulin requirements in diabetic |
|-Cephulac | | |-Reduce ammonia blood levels in the prevention |patients |
| | | |and treatment of hepatic encephalopathy. |-In patients with pre-existing fluid and |
| | | |-Laxative |electrolyte imbalances, lactulose may exacerbate |
| | | | |these if it causes diarrhea |
|Levamisole |Plumb’s pg. 615-617 |PO |-Antiparasitic, Immune stimulant |-Contraindicated in milk producing animals |
|-Levasole | | |-Antinematodal parasiticide that also may be |-Use cautiously, if at all, in severely |
|-Tramisol | | |useful in immune stimulant |debilitated, or significant renal or hepatic |
| | | | |impairment, in cattle that are stressed due to |
| | | | |vaccines, dehorning, or castration |
|Levothyroxine sodium |Plumb’s pg. 619-621 |PO |-Thyroid Hormone |-Contraindicated in those with acute myocardial |
|-Soloxine | | |-Treatment of hypothyroidism in all species. |infarction, thyrotoxicosis, or untreated adrenal |
|-Synthroid | | |-Has been used to treat equine metabolic syndrome|insufficiency |
| | | |in horses |-Caution with concurrent hypoadrenocorticism |
| | | | |(treated), cardiac disease, diabetes, or elderly |
| | | | |patients |
| | | | |-Drug-drug interactions and drug-lab interactions|
|Lidocaine |Plumb’s pg. 623-625 |IV, IO |-Antiarrhythmic/Local anesthetic |-Contraindicated in those with severe degrees of |
|-Xylocaine | | |-Local and topical anesthetic |SA, AV, or intraventricular heart block, or |
|-Lignocaine | | |-Treat ventricular arrhythmias |Adams-Strokes syndrome |
| | | | |-Caution: cats appear more sensitive to |
| | | | |cardiodepressant and CNS effected of lidocaine |
| | | | |-Drug interactions |
| | | | |-DO NOT use the product containing epinephrine IV|
| | | | |-When IV bolus given too rapidly, hypotension may|
| | | | |occur and seizures are possible |
|Diphenoxylate |Plumb’s pg. 344-345 |PO |-Opiate agonist/ anticholinergic |-Contraindicated: patients receiving MAOI’s, |
|-Lomotil | | |-GI motility modifier, primarily used as an |diarrhea caused by toxic ingestion until the |
| | | |antidiarrheal |toxin is eliminated from the GI tract, intestinal|
| | | | |obstruction |
| | | | |-Use is controversial in cats and many clinicians|
| | | | |do not recommend it’s use in this species |
|Loperamide |Plumb’s pg. 636-637 |PO |-Opiate Antidiarrheal |-Contraindicated in dogs with ABCB1-1 mutation, |
|-Imodium | | |-GI motility modifier used for symptomatic |diarrhea caused by a toxic ingestion until the |
| | | |treatment of diarrhea, primarily in dogs |toxin is eliminated from the GI tract, avoid use |
| | | | |if cause is due to an invasive microorganism |
| | | | |-Dose very carefully in small dogs and cats |
| | | | |-Use in cats is controversial and many clinicians|
| | | | |do not recommend it’s use in this species |
|Lufenuron |Plumb’s pg. 643-644 |PO, Injectable (cats, no |-Chitin Synthesis Inhibitor |-Cat labeled injectable products should not be |
|-Program | |route of injection given) |-Used for flea control in dogs and cats, |used on dogs, severe local reactions are possible|
| | | |potentially an antifungal agent |-No contraindications given |
|Lufenuron + milbemycin oxime |Plumb’s online |PO |-Chitin Synthesis Inhibitor, Macrolide |-Should have a negative HW test prior to |
|-Sentinel | | |Antiparasitic |administration |
| | | |-Used for flea, heartworm, roundworm, hookworm, |-Give with or just after a meal |
| | | |and whipworm control in dogs |-Pay close attention to package for age and |
| | | | |weight restrictions |
|L-lysine |Plumb’s pg. 644-645 |PO |-Nutritional Amino Acid; Anti-Feline Herpes Virus|There are no specific contraindications for this |
|-Lysine | | |-May be effective in suppressing FHV-1 infection |drug. Adverse reactions are unlikely when mixed |
| | | |in cats |with food. |
|Lutalyse |Plumb’s pg. 339-341 |SC, PO, IM |-Prostaglandin |-Contraindicated in pregnancy when abortion or |
|-Dinoprost Tromethamine | | |-Used as a luteolytic agent for estrous |induced parturition not wanted, manufacturer |
|Prostaglandin F2alpha | | |synchronization, pyometra treatment, and as an |lists several contraindications for horses, has |
|Tromethamine | | |abortifacient |been associated with serious toxicity and death |
| | | | |in camelids |
| | | | |-Do not administer IV, extreme caution in elderly|
| | | | |or debilitated animals |
| | | | |-Pregnant women should not handle, humans with |
| | | | |asthma and women of childbearing age should |
| | | | |handle with caution |
|Magnesium |Plumb’s pg. 645-647 |PO |-Oral antacid/Laxative |-Contraindicated in patients with renal disease. |
|Hydroxide | | |-Used as a gastric antacid for ulcers |-In cattle, the rumen pH should be determined |
| | | |-Can be useful to increase rumen pH |before use |
| | | | |-Magnesium salts may cause diarrhea |
| | | | |-Many potential drug interactions with orally |
| | | | |administrated drugs |
| Magnesium sulfate |Plumb’s pg. 647-650 |Iv, PO |-Parenteral Electrolyte |-Contraindicated with significant myocardial |
| | | |-For hypomagnesemia, for adjunctive therapy of |damage or heart block |
| | | |malignant hyperthermia in swine, as an |-Caution in those with impaired function |
| | | |anticonvulsant, and for refractory ventricular | |
| | | |arrhythmias | |
| Mannitol |Plumb’s pg. 650-651 |IV, IO |-Diuretic |-Should not be used in patients with anuria |
|-Osmitrol | | |-Used for oliguric renal failure, reduction of |secondary to renal disease, in patients that are |
| | | |intraocular and cerebrospinal fluid pressure, and|severely dehydrated, or in patients with |
| | | |rapid reduction of edema or ascites |pulmonary congestion or edema |
| | | | |-May cause fluid and electrolyte imbalances |
| Marbofloxacin |Wanamaker/Massey pg. 252 |PO |-Fluoroquiolone antibiotic |-May cause hypersensitivity and GI stress |
|-Marbocyl | | |-Effective against a variety of pathogens, no |-Not for use in young growing animals because of |
|-Zeniquin | | |efficacy against anaerobes |the potential for cartilage abnormalities |
| Maropitant |Plumb’s pg. 654-656 |SC, PO |-Neurokinin Receptor Antagonist Antiemetic |-Safety has not been tested in dogs or cats with |
|-Cerenia | | |-Vet FDA approved antiemetic for dogs and cats |GI obstruction or that have ingested toxins |
| | | | |-Use with caution with other medications that are|
| | | | |highly protein bound |
| | | | |-Use with caution in patients with hepatic |
| | | | |dysfunction |
| Meclizine |Wanamaker/Massey pg. 310 |PO |-Antiemetic |-Caution with prostatic hypertrophy, bladder neck|
|-Antivert | | |-Treatment and prevention of motion sickness |obstruction, severe cardiac failure, |
| | | | |angel-closure glaucoma, or pyoloduodenal |
| | | | |obstruction |
| Meclofenamic acid | |PO |-NSAID |-Do not use in those with gastric ulcers, or |
|-Arquel | | |-Joint and muscular pain, arthritis and |bleeding. |
| | | |dysmenorrhea |-Do not use in those with liver or kidney disease|
| Melarsomine |Plumb’s pg. 671-673 |Deep IM |-Arsenical Antiparasitic |-Contraindicated with class IV heartworm disease,|
|-Immiticide | | |-Treatment for heartworm disease in dogs. |very toxic in cats, weigh risks vs benefits in |
| | | | |pregnant, lactating, and breeding dogs |
| Meloxicam |Plumb’s pg. 675-677 |PO, IV, SC |-Nonsteroidal Anti-inflammatory Agent (NSAID) |-Safety not evaluated in dogs less than 6 months |
|-Metacam | | |-Treating pain, inflammation, and osteoarthritis |of age and cats less than 4 months of age |
| | | |in dogs. |-Use with extreme caution or avoid use in those |
| | | |-Post operative pain and inflammation associated |with active GI ulcerations, bleeding, or |
| | | |with orthopedic surgery, ovariohysterectomy and |receiving glucocorticoids. |
| | | |castration |-Use with caution in patients with impaired |
| | | | |hepatic, cardiac, or renal function and |
| | | | |hemorrhagic disorders. |
| Meperidine |Plumb’s pg. 680-682 |IM, SC, IV (give very slowly|-Opiate agent |-Contraindicated with hypersensitivity and |
|-Demerol | |IV) |-Short duration of analgesia |diarrhea caused by a toxic ingestion |
|-Pethidine | | | |-Use with extreme caution in those with |
| | | | |respiratory disease or acute respiratory function|
| | | | |-Caution in those with hypothyroidism, severe |
| | | | |renal insufficiency, adrenocortical |
| | | | |insufficiency, geriatric or severely debilitated |
| | | | |patients, head injuries or increased intracranial|
| | | | |pressure, and acute abdominal conditions |
| Methimazole |Plumb’s pg. 693-695 |PO, transdermal |-Antithyroid |-Use with caution in those with history of or |
|-Tapazole | | |-Treatment of feline hyperthyroidism |concurrent hematologic abnormalities, liver |
| | | | |disease, or autoimmune disease |
| | | | |-Contraindicated in those with hypersensitivity |
| | | | |to the drug |
| Methocarbamol |Plumb’s pg. 697-698 |IV (give slowly IV), PO |-Muscle Relaxant |-Contraindicated in food animals, renal disease |
|-Robaxin | | |-Centrally acting muscle relaxant, muscle tremors|(injectable only), and those with |
| | | |associated with toxic agents |hypersensitivity to it. |
| Methohexital |Plumb’s pg. 698-699 |IV |-Ultra-Short acting barbiturate |-Contradindicated in those with absence of |
|-Brevital | | |-Sometimes used in small animals for anesthetic |suitable veins for IV administration, history of |
| | | |agent and may be useful in sight hound breeds |hypersensitivity to barbiturates, status |
| | | | |asthmaticus, severe cardiovascular disease or |
| | | | |pre-existing ventricular arrhythmias, shock, |
| | | | |increased intracranial pressure, myasthenia |
| | | | |gravis, asthma, and conditions where hypnotic |
| | | | |effects may be prolonged |
| Methypredniso- |Plumb’s pg. 705-708 |PO, IM, IV |-Glucocorticoid |-Contraindicated in those with systemic fungal |
| | | |-Replacement of glucocorticoid activity in |infections, animals with arrested tuberculosis, |
|lone acetate | | |patients with adrenal insufficiency, an |peptic ulcer, acute psychoses, corneal ulcer, and|
|-Medrol | | |anti-inflammatory agent, an immunosuppressive |cushingoid syndrome |
|-Depo-Medrol | | | |-Use with caution in those with diabetes, |
| | | | |osteoporosis, chronic psychotic reactions, |
| | | | |predisposition to thrombophlebitis, hypertension,|
| | | | |CHF renal insufficiency, and active tuberculosis |
|Metoclopramide |Plumb’s pg. 710-712 |PO, IM, SC |-GI Prokinetic agent |-Contraindicated in those with GI hemorrhage, |
|-Reglan | | |-Stimulates upper GI motility, and has antiemetic|obstruction or perforation, and those with |
| | | |properties |seizure disorders or pheochromocytoma |
| | | | |-Potentially serious drug interactions |
| Metronidazole |Plumb’s pg. 715-717 |PO, IV |-Antibiotic, antiparasitic |-Contraindicated in those with hypersensitivity |
|-Flagyl | | |-Treatment of Giardia in dogs and cats, treatment|to the drug or other nitroimidazole derivatives. |
| | | |of other parasites in small animals |-Use with extreme caution in severely debilitated|
| | | | |patients, those who are pregnant or nursing, with|
| | | | |hepatic dysfunction |
| | | | |-May be teratogen, especially early in pregnancy |
| Midazolam |Plumb’s pg. 722-725 |SC, IV, IM, Intranasal |-Benzodiazepine |-Contraindicated in those with hypersensitivity |
|-Versed | | |-Used for sedative, anxiolytic, and muscle |to benzodiazepines, and acute narrow-angle |
| | | |relaxant properties |glaucoma. |
| | | |-May also be beneficial in treating status |-Use with caution in those with hepatic or renal |
| | | |epilepticus |disease, debilitated or geriatric patients, those|
| | | | |in a coma, shock, or with significant respiratory|
| | | | |depression |
| | | | |-Many drug interactions |
|Milbemycin oxime/ |Plumb’s online |PO |-Macrolide antiparasitic |-Should have a negative HW test before |
|Praziquantel | | |-Prevents heartworm disease and treats and |administration |
|-Interceptor Plus | | |controls adult hookworm, roundworm, whipworm, and|-Pay attention to package for weight and age |
| | | |tapeworm infections |restrictions |
| Minocycline |Plumb’s pg. 730-731 |PO |-Tetracycline antibiotic |-Drug and lab interactions |
|-Minocin | | |-May be useful in treating Brucellosis, Lyme |-Contraindicated in those with hypersensitivity |
| | | |disease, and with certain nosocomial infections |to tetracycline, those that are pregnant or |
| | | |where other more commonly used drugs are |nursing, or who are 6 months of age or younger |
| | | |ineffective |-Do not dry pill. Must be followed by sufficient |
| | | | |amounts of water |
| | | | |-Not recommended for UTI treatment |
| Morphine |Plumb’s pg. 743-746 |Parental, PO |-Opiate agonist |-Contraindicated in those with sensitivity to |
| | | |-Treatment of acute pain in dogs, cats, horses, |Morphine, diarrhea caused by a toxic ingestion |
| | | |swine, sheep, and goats |-Use with extreme caution in those with |
| | | |-Preanesthetic agent in several species |respiratory disease or from acute respiratory |
| | | |-Antitussive, antidiarrheal, and adjunctive |dysfunction |
| | | |therapy for some cardiac abnormalities |-Caution in those with hypothyroidism, severe |
| | | | |renal insufficiency, adrenocortical |
| | | | |insufficiency, geriatric or severely debilitated |
| | | | |patients, head injuries or increased intracranial|
| | | | |pressure, and acute abdominal conditions |
| Moxidectin |Plumb’s pg. 747-751 |Topical, SC, PO |-Avermectin Antiparasitic |Contraindications: dogs- hypersensitivity to the |
|-Cydectin | | |-Antiparasitic drug used for cattle, dogs, cats, |drug cattle- female dairy cattle of breeding age |
|-Pro-heart | | |ferrets, sheep, and horses |horses- intended for food purposes or in foals |
|-Advantage Multi | | |-Proheart 6: HW prevention in dogs |younger than 4 months of age |
| Naloxone |Plumb’s pg. 757-759 |IV, IM, SC, IO, IP |-Opiate Antagonist |-Caution in those with pre-existing cardiac |
|-Narcan | | |-Used almost exclusively for its opiate reversal |abnormalities or opioid dependent patients. Can |
| | | |effects |negate opioid analgesic effects. |
| | | |-Being tested for treating other conditions |-Reversal effects may last for a shorter time |
| | | | |period than the opioid effect. May need to |
| | | | |re-dose…monitor appropriately |
| Nitenpyram |Plumb’s pg. 770-771 |PO, (reptiles- as enema, or |-Oral Insecticide |-Not effective on flea eggs or other immature |
|-Capstar | |on wound) |-Flea adulticide in dogs and cats |forms. |
| | | | |-Does not work on ticks |
| Nitroglycerin |Plumb’s pg. 773-774 |Topically |-Venodilator; Afterload Reducer |-Continuous use results in tolerance after 48-72 |
|Ointment | | |-Used for CHF or hypertension |hours |
|-NTG | | | |-Rotate application sites |
|-Nitro-Bid | | | |-Wear gloves when applying; avoid human skin |
|-Minitran | | | |contact |
|Oclacitinib |Plumb’s pg. 782-783 |PO |-Antipruritic, Janus Kinase (JAK) Inhibitor |-Not for use in dogs less than 12 months of age, |
|-Apoquel | | |-Control of pruritus associated with allergic |those with serious infections, breeding dogs, or |
| | | |dermatitis and control of atopic dermatitis |pregnant/lactating bitches |
| Omeprazole |Plumb’s pg. 785-787 |PO |-Proton Pump Inhibitor |-Contraindicated in patients with hepatic or |
|-Prilosec | | |-Used for GI ulcers and erosions |renal disease |
|-Gastrogard | | | | |
| Ondansetron |Plumb’s pg. 787-788 |PO, IV, SC, IM |-5 HT3 Receptor Antagonist |-May mask ileus or gastric distension, should not|
|-Zofran | | |-Antiemetic used for severe vomiting in dogs and |be used in place of nasogastric suction |
| | | |cats |-Use with caution in patients with hepatic |
| | | | |dysfunction |
| Orbifloxacin |Plumb’s pg. 788-790 |PO |-Fluoroquinolone Antibiotic |-Contraindicated in immature dogs during the |
|-Orbax | | |-Use in dogs and cats for susceptible bacterial |rapid growth phase |
| | | |infections. May also be beneficial in treating |-Caution with known or suspected CNS disorders |
| | | |gram-positive infections in horses are |-Drug interactions |
| | | |susceptible to the drug | |
|Orbifloxacin/ |Plumb’s online |Otic |-Antifungal, Fluoroquinolone Antibiotic, |-Check tympanic membrane before use |
|Mometasone/ |Merck online | |Antipruritic/Antiinflammatory |-Not tested in pregnant, nursing, or lactating |
|Posaconazole | | |-Treatment of otitis externa |dogs |
|-Posatex | | | | |
| Oxazepam |Plumb’s online |PO |-Benzodiazepine |Contraindicated in those with acute narrow angle |
|-Serax | | |-Primarily an appetite stimulant in cats, but may|glaucoma |
| | | |also be used to treat behavior problems in dogs |-Caution in those with myasthenia gravis, hepatic|
| | | |or cats |dysfunction, and seizure disorders |
| Oxymorphone |Plumb’s pg. 799-801 |IV, IM, SC |-Opiate Agonist |-Caution in patients with hypothyroidism, severe |
|-Numorphan | | |-Used in dogs and cats as a sedative/restraining |renal insufficiency, adrenocortical |
| | | |agent, analgesic, and pre-anesthetic |insufficiency, and in geriatric or severely |
| | | |-Occasionally in horses as an analgesic and |debilitated patients. |
| | | |anesthesia induction agent |-Use with extreme caution in patients with head |
| | | | |injuries, increased intracranial pressure, and |
| | | | |acute abdominal conditions, patients suffering |
| | | | |from respiratory disease or acute respiratory |
| | | | |dysfunction |
| Oxytocin |Plumb’s pg. 806-808 |SC, IM, IV |-Hormonal Agent |-Contraindicated in those with dystocia due to |
|-Pitocin | | |-Induction or enhancement of uterine contractions|abnormal presentations of fetus(es) unless |
| | | |at parturition, postpartum retained placenta and |correction is made. When used pre-partum, use |
| | | |metritis, uterine involution after manual |only when cervix is relaxed |
| | | |correction or prolapsed uterus in dogs and |-Treat hypoglycemia or hypocalcemia before use |
| | | |agalactia |-Drug interactions |
|Oxytetracycline |Plumb’s pg. 802-804 |IV, PO, IM, SC |-Tetracycline Antibiotic |-Extreme caution in those with pregnancy |
|-Terramycin | | |-Treatment of Mycoplasma, Rickettsia, |-Caution with liver, renal insufficiency |
| |Plumb’s online | |Spirochetes, and Chlamydia |-Withdrawal times in food animals |
|Panolog |Plumb’s online |Topical |-Dermatologic drug |-Very safe |
|-Nystatin | | |-Used in combination with other creams for |-Clients should wear gloves or wash hands |
| | | |treatment of yeast-lesions and mixed otitis |thoroughly after applying |
| | | |infections | |
| Pancrelipase |Plumb’s pg. 812-813 |PO |-Pancreatic Enzyme |-Contraindicated in those with sensitivity to |
|-Viokase | | |-Treat exocrine pancreatic enzyme deficiency or |pork products. |
|-Lipase/Portease/Amylase | | |to test for pancreatic insufficiency secondary to|-Avoid inhalation of powder, may cause skin |
| | | |chronic pancreatitis |irritation, wash off if gets on hands |
| Paroxetine |Plumb’s pg. 820-21 |PO |-Selective Serotonin Reuptake Inhibitor |-Contraindicated in patients receiving monoamine |
|-Paxil | | |Antidepressant |oxidase inhibitors |
| | | |-Treatment of canine aggression, and stereotypic |-Caution in patients with severe cardiac, renal, |
| | | |or other obsessive compulsive behaviors |or hepatic disease |
| Penicillin-G |Plumb’s pg. 825-827 |IV, IM, SC, PO |-Penicillin Antibiotic |-Contraindicated in those with hypersensitivity |
| | | |-Used to treat susceptible gram-positive aerobes |to the drug, unless there are no other options |
| | | |and anaerobes |-Certain species may be sensitive to procaine |
| | | | |Penicillin-G |
| Pentobarbital |Plumb’s pg. 832-834 |IV (give SLOWLY), IP |-Barbiturate |-Contraindicated in those with severe liver |
|-Nembutal | | |-Used therapeutically as a sedative/anesthetic, |disease, nephritis, or severe respiratory |
| | | |and treating intractable seizures, also used for |depression |
| | | |euthanasia |-Caution in those with hypovolemia, anemia, |
| | | | |borderline hypoadrenal function, or cardiac or |
| | | | |respiratory disease |
| | | | |-Use with caution in cats |
| | | | |-Numerous drug interactions |
| Phenobarbital |Plumb’s pg. 840-842 |PO, IV (give SLOWLY) |-Barbiturate |-Contraindicated in those with severe liver |
|-Phenobarbitone | | |-Used primarily as an anti-seizure medication, |disease, nephritis, or severe respiratory |
| | | |also used as a sedative agent |depression |
| | | | |-Caution in those with hypovolemia, anemia, |
| | | | |borderline hypoadrenal function, or cardiac or |
| | | | |respiratory disease |
| | | | |-Use with caution in cats |
| | | | |-Do NOT give SC or perivascularly |
| | | | |-Drug interactions, drug-lab interactions |
| Phenylbutazone |Plumb’s pg. 845-847 |IV, PO |-Non-steroidal anti-inflammatory Agent |-Contraindicated in those with pre-existing |
|-Bute | | |-Treatment of pain and inflammation in horses, |hematologic or bone marrow abnormalities, |
|-Butazolidin | | |has been used in other species like dogs, cattle,|pre-existing GI ulcers, in food producing animals|
| | | |swine |-Caution in foals or ponies, pre-existing CHF or |
| | | | |renal disease |
|Phenylpropanol- |Plumb’s pg. 849-850 |PO |-Sympathomimetic |-Caution in those with glaucoma, prostatic |
|Amine | | |-Used primarily for urethral sphincter hypotonus |hypertrophy, hyperthyroidism, diabetes mellitus, |
|-PPA | | | |cardiovascular disorders, or hypertension |
|-Proin | | | | |
|Pimobendan |Plumb’s pg. 858-860 |PO |-Inodilator |-Give on empty stomach |
|-Vetmedin | | |-May be useful in treatment of congestive heart |-May increase risks for arrhythmia |
| | | |failure in dogs |-Contraindicated in animals with hypertrophic |
| | | | |cardiomyopathy, aortic stenosis, or any other |
| | | | |condition where an increase of cardiac output is |
| | | | |inappropriate for function or anatomic reasons |
| Piroxicam |Plumb’s pg. 865-866 |PO |-Non-Steroidal Anti-inflammatory agent, |-Contraindicated in those that are severely |
|-Feldene | | |Anti-tumor |allergic to aspirin or other NSAIDs |
| | | |-Primarily used for its anti-tumor activity |-Extreme caution in those with active or a |
| | | | |history of GI ulcer disease or bleeding disorders|
| | | | | |
| | | | |-Caution in those with severely compromised |
| | | | |cardiac function |
| Pitressin(ADH) |Plumb’s pg. 1079-1081 |IM, IV, IO |-Anti-diuretic hormone, Pressor agent |-Contraindicated in those with chronic nephritis |
|-Vasopressin | | |-Hormone used primarily as a diagnostic agent and|until nitrogen retention is resolved to |
| | | |for the adjunctive treatment of shock syndrome |reasonable levels, or patients hypersensitive to |
| | | |and cardiopulmonary-cerebral resuscitation (CPCR)|the drug |
| | | | |-Caution in those with vascular disease, seizure |
| | | | |disorders, heart failure, or asthma |
|Ponazuril |Plumb’s pg. 869-870 |PO |-Anti-protozoal |-No contraindications were noted |
|-Marquis | | |-FDA approved for treating EPM |-Before treating, other conditions that can cause|
|-Toltrazuril | | |-Could potentially be useful in treating Neospora|ataxia should be ruled out |
| | | |caninum and Toxoplasma or other protozoal | |
| | | |infections in other species like cats, dogs, | |
| | | |birds, reptiles, and ruminants | |
| Polysulfated |Plumb’s pg. 868-869 |IM, IA, SC, IM |-Proteolytic Enzyme Inhibitor, Chonroprotectant |-Contraindications: IA injection if patient is |
|Glycosaminoglycan | | |-Non-infectious and/or traumatic joint |hypersensitive to PSGAG. Should not be used in |
|-Adequan | | |dysfunction and associated lameness of the carpal|place of other treatments when infection |
|-Chondroprotec | | |joints in horses, and non-infectious degenerative|suspected or present, or when surgery or joint |
| | | |and/or traumatic arthritis in dogs |immobilization is required |
|Potassium bromide |Plumb’s pg. 120-121 |PO |-Anticonvulsant |-Do not feed salty snacks, keep chloride diet |
| | | |-Primary or adjunctive therapy for seizure |stable |
| | | |disorders in dogs, rarely used in cats- can cause|-Patients with renal dysfunction may require |
| | | |eosinophilic bronchitis |dosage adjustments |
| | | | |-Extreme caution or avoidance in cats |
| Potassium glucon- |Plumb’s pg. 872-874 |PO, IV (give slowly) |-Electrolyte |-Contraindications in those with hyperkalemia, |
|Ate | | |-Treatment or prevention of hypokalemia |renal failure or severe renal impairment, severe |
| | | | |hemolytic reactions, untreated Addison’s disease,|
| | | | |acute dehydration, GI motility impairment |
| | | | |-Caution with patients on digoxin |
| | | | |-Drug interactions |
| Pralidoxime chlor- |Plumb’s pg. 877-878 |IV, SC, IM |-Antidote, Cholinesterase Reactivator |-Contraindications: hypersensitivity to the drug,|
|ide (2-PAM) | | |-Adjunctive treatment of organophosphate |not recommended for carbamate poisoning |
|-Protopam Chloride | | |poisoning |-Caution in those with renal impairment, patients|
| | | | |receiving anticholinesterase agents for treatment|
| | | | |of myasthenia gravis |
| | | | |-Most effective if given within 24 hours of |
| | | | |exposure |
| Praziquantel |Plumb’s pg. 879-881 |PO, SC, IM |-Anti-cestodal, anti-parasitic |-Contraindicated in puppies less than 4 weeks old|
|-Droncit | | |-Anthelmintic |and kittens less than 6 weeks old |
| Prednisolone |Plumb’s pg. 883-885 |PO, IV, IM |-Glucocorticoid, anti-inflammatory |-Contraindicated in those with systemic fungal |
| | | |-Replacement or supplementation of glucocorticoid|infections |
| | | |effects secondary to hypoadrenocorticism |-Caution in bacterial infections, corneal ulcers,|
| | | |-Anti-inflammatory |cushingoid syndrome, diabetes, osteoporosis, |
| | | |-An immunosuppressive |chronic psychotic reactions, predisposition to |
| | | |-Anti-neoplastic agent |thrombophlebitis, hypertension, CHF, renal |
| | | | |insufficiency |
| | | | |-Many potential drug and lab interactions |
|Procainamide |Plumb’s pg. 894-895 |IV, IM |-Anti-arrhythmic |-Contraindications: myasthenia gravis, |
|-Pronestyl | | |-Used primarily for treatment of atrial |hypersensitivity to the drug, procaine, or other |
| | | |fibrillation, ventricular premature complexes |chemically related drugs, 2nd or 3rd degree heart|
| | | |(VPC), ventricular tachycardia |block |
| | | | |-Extreme caution in those with cardiac glycoside |
| | | | |intoxication, systemic lupus |
| | | | |-Caution with significant hepatic disease, renal |
| | | | |disease, or CHF |
| | | | |-Drug interactions |
| | | | |-Intense hypotension can occur if injected too |
| | | | |rapidly IV |
| Propantheline |Plumb’s pg. 901-902 |PO, IV |-Quaternary Antimuscarinic |-Contraindicated in those with hypersensitivity |
|Bromide | | |-Used for anti-spasmodic/antisecretory effects |to anticholinergics, tachycardias secondary to |
|-Pro-Banthine | | |for the treatment of diarrhea, hyperreflexic |thyrotoxicosis or cardiac insufficiency, |
| | | |detrusor, or urge incontinence and |myocardial ischemia, unstable cardiac status |
| | | |anticholinergic responsive bradycardias. |during acute hemorrhage, GI obstructive disease, |
| | | |-In horses, to reduce colonic peristalsis and |paralytic ileus, severe ulcerative colitis, |
| | | |relax rectum to allow easier examination and |obstructive uropathy, or myasthenia gravis |
| | | |surgery |-Extreme caution in those with known or suspected|
| | | | |GI infections, autonomic neuropathy |
| | | | |-Caution in those with hepatic or renal disease, |
| | | | |hyperthyroidism, hypertension, CHF, |
| | | | |tachyarrhythmias, prostatic hypertrophy, |
| | | | |esophageal reflux, and geriatric or pediatric |
| | | | |patients |
| Propofol |Plumb’s pg. 904-907 |IM, SC, IV |-Anesthetic |-Contraindicated in those with hypersensitivity |
|-Rapinovet | | |-Induction agent |to it or any component of the product |
|-PropoFlo | | |-Anesthetic for outpatient diagnostic or minor |-Caution in patients with severe stress or having|
|-Diprivan | | |procedures |undergone trauma, hypoproteinemia, |
| | | |-Treatment for refractory status epilepticus |hyperlipidemia, seizures, or anaphylaxis history |
| Propanolol |Plumb’s pg. 908-910 |IV, PO, SC |-Beta-Adrenergic Blocker |-Contraindicated in those with heart failure, |
|-Inderal | | |-Primarily used as an anti-arrhythmic agent |greater than 1st degree heart block, or sinus |
| | | |-Sometimes used for short-term treatment of |bradycardia |
| | | |clinical signs associated with thyrotoxicosis or |-Generally contraindicated in patients with CHF |
| | | |pheochromocytoma |unless secondary to tachyarrhythmia responsive to|
| | | | |beta-blockers or with bronchospastic lung disease|
| | | | |-Caution in those with significant renal or |
| | | | |hepatic insufficiency, sinus node dysfunction, |
| | | | |labile diabetic patient, digitalized or digitalis|
| | | | |intoxicated patients |
| | | | |-Drug interactions |
| Prostglandin F2 |Plumb’s pg. 339-341 |SC, IM |-Prostaglandin |-DO NOT AMINISTER IV |
|Alpha | | |-Estrous synchronization, pyometra treatment, or |-Contraindicated in pregnant patients when |
|-Lutalyse | | |as an abortifacient |abortion or induction is not intended |
| | | | |-Use with extreme caution in elderly or |
| | | | |debilitated animals |
| | | | |-Pregnant women should not handle this drug, |
| | | | |humans with asthma, or of childbearing age should|
| | | | |handle with caution |
| Psyllium |Plumb’s pg. 913-914 |PO |-Bulk Forming GI laxative/ Anti-diarrheal |-Contraindicated in rabbits, where prompt |
|-Metamucil | | |-Treatment and prevention of sand colic in |intestinal evacuation is required, or when fecal |
| | | |horses, as a laxative and to increase stool |impaction or intestinal obstruction is present |
| | | |consistency in patients with chronic, watery | |
| | | |diarrhea | |
| Pyrantel pamoate |Plumb’s pg. 914-915 |PO |-Anti-parasitic |-Contraindicated in severely debilitated animals |
|-Strongid T | | |-Anthelmintic used primarily for ascarids in a | |
|-Nemex | | |variety of species | |
|Quinidine |Plumb’s pg. 925-927 |PO, IM, IV |-Anti-arrhythmia |-Contraindicated in patients with myasthenia |
| | | |-Used in small animals and horses for arrhythmias|gravis, complete AV block with an AV junctional |
| | | | |or indioventricular pacemaker, intraventricular |
| | | | |conduction defects, digitalis intoxication with |
| | | | |associated arrhythmias, or AV conduction |
| | | | |disorders, aberrant ectopic impulses, or abnormal|
| | | | |rhythms secondary to escape mechanisms |
| | | | |-Extreme caution in those with any form of AV |
| | | | |block or if any clinical signs of digoxin |
| | | | |toxicity are exhibited |
| | | | |-Caution in those with uncorrected hypokalemia, |
| | | | |hypoxia, and disorders or acid-base balance, |
| | | | |hepatic or renal insufficiency |
| Ranitidine |Plumb’s pg. 929-930 |PO, SC, IM, IV (slowly) |-H2 Receptor Antagonist, Prokinetic |-Caution in geriatric patients or those with |
|-Zantac | | |-Reduce acid output in stomach |hepatic or renal insufficiency |
| | | | |-Contraindicated in those with hypersensitivity |
| | | | |to the drug |
|Robenacoxib |Plumb’s pg. 935-937 |PO, SC |-NSAID |-Contraindicated in patients with intolerance to |
|-Onsior | | |-For use in cats and dogs, control of |NSAIDs, or with GI ulcers, and in dogs with |
| | | |postoperative pain and inflammation associated |hepatic disease |
| | | |with orthopedic surgery, ovariohysterectomy, and |-Use with caution in patients with impaired |
| | | |castration |cardiac or renal function, or that are |
| | | | |dehydrated, hypovolemic, or hypotensive, and in |
| | | | |cats- with hepatic dysfunction |
| | | | |-Should not be used concurrently with |
| | | | |corticosteroids or other NSAIDs |
|Selamectin |Plumb’s pg. 949-950 |Topical |-Avermectin Antiparasitic |-Contraindicated in sick, underweight, or |
|-Revolution | | |-Indicated for flea infestations, prevention of |debilitated dogs and cats |
| | | |heartworm disease, ear mites, sarcoptic mange, |-Use with caution in collie-type breeds |
| | | |tick infestations, (Cats) hookworm and roundworm | |
| Selegiline |Plumb’s pg. 951-952 |PO |-Monoamine Oxidase Inhibitor |-Drug interactions, some may be serious |
|-I-deprenyl | | |-May be useful for cognitive dysfunction syndrome| |
|-Anipryl | | |in dogs or cats, or in canine cushing’s | |
|-Elderpyrl | | | | |
|Sevoflurane |Plumb’s pg. 955-956 |PO via inspiration |-Inhalational Anesthetic |-Contraindicated in patients with a history or |
|-SevoFlo | | |-Rapid induction and/or rapid recoveries |predilection towards malignant hyperthermia |
|-Ultane | | | |-Use with caution in patients with increased CSF,|
| | | | |head injury, or renal insufficiency. Use with |
| | | | |caution in rabbits and guinea pigs |
| Silymarin |Plumb’s pg. 959-960 |PO |-Hepatoprotectant |-Potential drug interactions |
|-Milk Thistle | | |-May be useful for treatment of chronic and acute|-No reported absolute contraindications |
|-Silybin | | |liver disease, cirrhosis, or as a | |
|-Marin | | |hepto-protective agent when hepatotoxins ingested| |
| Sucralfate |Plumb’s pg. 983-984 |PO |-GI Mucosal Protectant |-No contraindications |
|-Carafate | | |-Treatment of GI ulcers/esophagitis, may also |-Caution where decreased GI transit times may be |
| | | |protect somewhat against GI ulceration, could |harmful |
| | | |potentially be useful in lowering serum |-Give on empty stomach if possible |
| | | |phosphorus in renal patients |-Drug interactions |
| Sufadiazine/trim- |Plumb’s pg. 988-990 |PO |-Potentiated Sulfonamide Antimicrobial |-Contraindicated in those with sulfa, thiazide, |
|Methoprim | | |-Treatment of susceptible organisms |or sulfonylurea agent sensitivities, severe |
|-TMS | | | |renal, or hepatic impairment, or in Doberman |
|-Co-trimoxazole | | | |pinschers |
|-Tribrissen | | | |-Caution in those with diminished renal or |
| | | | |hepatic function or urinary obstruction or |
| | | | |urolithiasis |
| Sulfadimethoxine |Plumb’s pg. 992-993 |PO, IV |-Sulfonamide Antimicrobial |-Contraindicated in those with hypersensitivity |
|-Albon | | |-Usually used for coccidiosis |to sulfas, thiazides, or sulfonyrea agents, those|
| | | | |with severe hepatic or renal impairment, or in |
| | | | |Doberman pinschers |
| | | | |-Caution in those with diminished renal or |
| | | | |hepatic function, or urinary obstruction |
| Tiletamine + |Plumb’s pg. 1030-1032 |IV, IM |-Anesthetic/Tranquilizer |-Contraindicated in those with pancreatic |
|Zolazepam | | |-Indicated for restraint or anesthesia combined |disease, rabbits, severe cardiac disease, use in |
|-Telazol | | |with muscle relaxant , or for restraint and minor|cesarean section, or pulmonary disease |
| | | |procedures for short duration |-Caution in those with renal disease, large |
| | | | |exotic cats, especially tigers |
| | | | |-Monitor body temperature, may cause hypothermia |
| Tetracycline |Plumb’s pg. 1010-1012 |PO |-Tetracycline Antibiotic |-Extreme caution in pregnancy |
| | | |-Many bacteria are now resistant to this drug, |-Caution with liver or renal insufficiency |
| | | |but still may be useful to treat mycoplasma, | |
| | | |rickettsia, spirochetes, and chlamydia | |
| Theophylline |Plumb’s pg. 1013-1014 |PO |-Phosphodiesterase Inhibitor Bronchodilator |-Many drug interactions |
| | | |-Dilates bronchioles and may have mild diuretic |-Use with caution in patients with severe cardiac|
| | | |activity |disease, seizure disorders, gastric ulcers, |
| | | |-Used short-term for bronchospasms and |hyperthyroidism, renal or hepatic disease, severe|
| | | |cardiogenic pulmonary edema |hypoxia, or severe hypertension |
| Tobramycin |Plumb’s pg. 1039-1041 |IV, IM, SC |-Aminoglycoside Antibiotic |-Cats may be more sensitive to toxic effects |
|-TOBI | | |-Good activity against a variety of bacteria, |-Should use caution in patients with |
|-Nebcin | | |mainly gram-negative aerobic bacilli |neuromuscular disorders |
| | | | |-Caution in working dogs due to irreversible |
| | | | |ototoxicity |
| | | | |-Contraindicated in rabbits/hares |
|Toceranib phosphate |Plumb’s pg. 1042-1043 |PO |-Tyrosine Kinase Inhibitor Antineoplastic |-Essential monitoring is required |
|-Palladia | | |-FDA-approved for grades 2 or 3 canine mast cell | |
| | | |tumors | |
| Tramadol hydro- |Plumb’s pg. 1052-1054 |PO, IV |-Opiate Like Agonist |-Use with caution in conjunction with other drugs|
|Chloride | | |-Inhibits reuptake of serotonin and |that can cause CNS or respiratory depression |
|-Ultram | | |norepinephrine | |
| | | |-May be useful for post-operative, chronic pain, | |
| | | |or cough in dogs and cats | |
| Triamcinolone |Plumb’s pg. 1057-1060 |PO, topical, IM, SC |-Glucocorticoid |-Contraindicated with systemic fungal infections,|
|-Vetalog | | |-Treatment of inflammation and related disorders |viral infections, animals with arrested |
| | | |in dogs, cats, and horses |tuberculosis, peptic ulcers, acute psychoses, |
| | | |-Indicated for use in dogs and cats for the |corneal ulcer, and cushingoid syndrome, the |
| | | |management and treatment of acute arthritis |presence of diabetes, osteoporosis, chronic |
| | | |allergic and dermatologic disorders |psychotic reactions, predisposition to |
| | | | |thrombophlebitis, hypertension, CHF, renal |
| | | | |insufficiency, and active tuberculosis |
| | | | |necessitates |
| | | | |-Many potential drug and lab interactions |
|Tiamulin |Plumb’s online |PO |-Diterpine Pleuromutilin Antibiotic |-Contraindicated in those weighing over 250lbs |
|-Denagard | | |-Antibiotic primarily used in swine for pneumonia|and those with access to feeds containing |
| | | | |polyether ionphores |
| Trilostane |Plumb’s pg. 1063-1064 |PO |-Adrenal Steroid Synthesis Inhibitor |-Use with caution in patients with renal or |
|-Vetoryl | | |-May be useful in dogs for treatment of |hepatic impairment |
| | | |pituitary-dependent hyperadrenocorticism, adrenal|-Contraindicated in pregnant dogs |
| | | |dependent hyperadrenocrticism, alopecia in |-If using for clinical signs of cushing’s in dogs|
| | | |Pomeranians and Alaskan malamutes, in cats- |with adrenal tumors, trilostane will not shrink |
| | | |treatment of feline pituitary dependent |the tumor and adrenal glands may actually |
| | | |hyperadrenocorticism, and in horses- equine |increase the size during treatment |
| | | |hyperadrenocorticism | |
|Tulathromycin |Plumb’s pg. 1069-1070 |SC, IM |-Macrolide Antibiotic |-Not for lactating dairy cattle or veal calves |
|-Draxxin | | |-Treating bovine respiratory disease, control of |-Cattle intended for human consumption cannot be |
| | | |respiratory disease. Also approved for the |slaughtered within 18 days of treatment |
| | | |treatment of bovine foot rot. Treatment of swine |-Swine intended for human consumption must not be|
| | | |respiratory disease. |slaughtered within 5 days from the last treatment|
| Ursodiol |Plumb’s pg. 1073-1074 |PO |-Bile Acid |-Contraindicated in rabbits and other hindgut |
|-Actigall | | |-Useful as adjunctive therapy for the medical |fermenters |
|-Ursodeoxycholic Acid | | |management of gallbladder mucocele and/or chronic|-Caution in complications associated with |
| | | |liver disease |gallstones |
| Vasopressin(ADH) |Plumb’s pg. 1079-1081 |IV, IO, IM |-Pressor Agent; Hormone |-Contraindicated in chronic nephritis until |
|-Pitressin | | |-Primarily used as a diagnostic agent and for the|nitrogen retention is resolved to reasonable |
|-Arginine Vasopressin | | |adjunctive treatment of shock syndromes and |levels. |
|-Antidiuretic hormone | | |cardiopulmonary-cerebral resuscitation |-Caution in vascular disease, seizure disorders, |
| | | | |heart failure, or asthma |
| Vincristine |Plumb’s pg. 1087-1089 |IV |-Anti-neoplastic |-Caution in those with hepatic disease, |
|-Oncovin | | |-used for a variety of tumors in dogs and cats, |leukopenia, infection or pre-existing |
| | | |also used for the treatment of immune-mediated |neuromuscular disease |
| | | |thrombocytopenia |-Drug interactions |
| | | | |-Wear gloves and protective clothing when |
| | | | |preparing or administering |
| Vitamin B12 |Plumb’s pg. 265-266 |SC, IM |-Vitamin/Nutritional |-No contraindications are documented for domestic|
|-Cyanocobalamin | | |-Vitamin B12 deficiency |animals |
| Vitamin K1 |Plumb’s pg. 857-858 |IM, SC, PO |-Antidote; Fat soluble Vitamin |Contraindications- dose not correct |
|-Mephyton | | |-Treatment of anticoagulant rodenticide toxicity,|hypoprothrombinemia due to hepatocellular damage |
| | | |dicumarol toxicity associated with sweet clover |-May require 6-12 hours for effect |
| | | |ingestion in ruminants, sulfaquinoxaline |-Small gauge needles are recommended |
| | | |toxicity, and bleeding disorders associated with | |
| | | |faulty formation of vitamin k dependent | |
| | | |coagulation factors | |
| Warfarin |Plumb’s pg. 1097-1098 |PO |-Anticoagulant |-Requires careful monitoring and dosage |
|-Coumadin | | |-Primarily used for long-term thromboprophylaxis |adjustments |
| | | |(primarily in dogs) |-Contraindicated in cats, pre-existing |
| | | | |hemorrhage, pregnancy, those undergoing or |
| | | | |contemplating eye or CNS surgery, major regional |
| | | | |lumbar block anesthesia, surgery of large, open |
| | | | |surfaces, acting bleeding from the GI, |
| | | | |respiratory, or GU tract, aneurysm, acute |
| | | | |nephritis, cerebrovascular hemorrhage, blood |
| | | | |dyscrasias, uncontrolled or malignant |
| | | | |hypertension, hepatic insufficiency, pericardial |
| | | | |effusion, and visceral carcinomas |
| | | | |-Many potential drug interactions |
| Xylazine |Plumb’s pg. 1099-1103 |IM, SC, IV |-Alpha-2 Adrenergic Agonist |-Contraindicated in animals receiving epinephrine|
|-Rompun | | |-Used for its sedative and analgesic properties |or having active ventricular arrhythmias |
| | | | |-Extreme caution in pre-existing cardiac |
| | | | |dysfunction hypotension or shock, respiratory |
| | | | |dysfunction, severe hepatic or renal |
| | | | |insufficiency, pre-existing seizure disorders, or|
| | | | |if severely debilitated |
| | | | |-Generally should not be used during the last |
| | | | |trimester of pregnancy. DO NOT give to |
| | | | |debilitated ruminants, dehydrated or with urinary|
| | | | |obstruction |
| | | | |-Horses can still kick! |
| | | | |-Caution in patients treated for intestinal |
| | | | |impactions |
|Yohimbine |Plumb’s pg. 1104-1105 |IV (slowly), IP, IM |-Alpha-2 Adrenergic Antagonist |-Drug interactions |
|-Yobine | | |-Used to reverse xylazine, may be used |-Caution in those with renal disease, seizure |
|-Antagonil | | |prophylactically before amitraz dips |disorder, possible that reversal effects will |
| | | | |diminish before the agonists effects dissipate |
|Zylkene |Zylkenepet.co.uk |PO |-Milk protein |-No contraindications |
| | | |-Helps cats and dogs adapt to uncomfortable | |
| | | |surroundings (groomers, fireworks, moving, new | |
| | | |pet/baby, etc) | |
| | | | |
References
Canine and Feline Gastroenterology - Robert J. Washabau, Michael J. Day - Google Books. (n.d.). Retrieved from
Home. (n.d.). Retrieved from
Interceptor® Plus (milbemycin oxime/praziquantel). (n.d.). Retrieved from
Ipecac Syrup (Oral Route) Description and Brand Names - Mayo Clinic. (n.d.). Retrieved from
Ipecac. (n.d.). Retrieved from
Meclofenamic Acid for Horses | EquiMed - Horse Health Matters. (n.d.). Retrieved from
Plumb, D. C. (2011). Plumb's veterinary drug handbook. Stockholm, Wis: PharmaVet.
Saunders Handbook of Veterinary Drugs: Small and Large Animal - Mark G. Papich - Google Books. (n.d.). Retrieved from
US. : Producers : Dairy : Products : Cystorelin. (n.d.). Retrieved from
Wanamaker, B. P., & Massey, K. L. (2015). Applied pharmacology for veterinary technicians.
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