How antibiotics kill bacteria: from targets to networks

bacteria (for example, Streptococcus pneumoniae21), whereas in Gram-negative bacteria (for example, Escherichia coli13 and Neisseria gonorrhoea22) their pri-mary target is topoisomerase II (and topoisomerase Iv is the secondary target). Introduction of DNA breaks and replication fork arrest. The ability of quinolone antibiotics to kill bacteria is ................
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