Intern Handbook Questions:

does not need to be de-methylated by liver / best choice for liver disease ... not great on gram negatives) / has stenotrophomonas activity that pip/tazo does not. Zosyn (piperacillin, tazobactam) ... (which explains the long half-life), but blood levels may not be high enough to cover bacteremias (which may happen with a pneumonia) ... ................
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