Substances that elicit positive and false-positive results using ...

[Pages:2]Substances that elicit positive and false-positive results using Siemens EMIT II Plus reagents

Siemens Emit? II Plus Amphetamines Assay (300ng Cutoff) Calibrated with d-Methamphetamine at 300 ng/ml

Drug

MDEA d,l-Amphetamine d,l-Methamphetamine 1-Amphetamine d-Amphetamine 1-Methamphetamine Methylenedioxyamphetamine (MDA) Methylenedioxymethamphetamine (MDMA) 1,3 Dimethylpentylamine

d,l-4-Methylamphetamine

ng/ml 4,400 625 450 3,450 300 725 1,100

5,200 3,400 4,400

Known False Positives Benzphetamine1 Bupropion 4-Chloroamphetamine

Chloroquine

Erythro-Dihydrobupropion l-Ephedrine Fenfluramine Donepezil Isomethetene Mephentermine Methoxyphenamine Nor-pseudoephedrine Phenmetrazine Phentermine Phenylpropanolamine (PPA) Propranolol d,l Pseudoephedrine Quinacrine

Selegiline (Eldepryl) Tranylcypromine Tyramine

400 250,000 26,000

2,100,000

20,000 400,000 25,000 64,000 16,000

8,000 90,000 40,000 23,000 58,000 700,000 100,000 1,400,000 2,500,000

2

30,000 150,000

1 Benzphetamine is metabolized to amphetamine and methamphetamine. 2 Selegiline is metabolized to l-amphetamine and l-methamphetmine

Emit? d.a.u. Amphetamine Class Assay calibrated with d-Amphetamine at 300 ng/ml

Drug d-Amphetamine d,1-Amphetamine d-Methamphetamine

ng/ml 300 300 1,000

Known False Positives D,1-Ephedrine Diethlpropion Isometheptene Isoxsuprine Mephentermine Nylidrin Phenelzine Phenmetrazine Phenylephrine Phentermine Phenylpropanolamine (PPA) Pseudoephedrine Tranylcypromine Labetalol Phenelzine N,N-dibenzylethylenediamine

1,000 unk 500 6,000 400 2000 unk 1,000 unk 400 1,000 unk 500 unk unk unk

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