BODY QUEST PART II
BODY QUEST PART II
You have designed a vessel that you feel will be able to withstand all the attacks put on Sam's body and you are now ready to have it inserted into Sam’s body. You contact the Doctor and he says he needs a detailed map of the journey your vessel will follow incase something goes wrong. In order to make the vessel small enough it had to be made with radioactive material that could be toxic to Sam if left into his body more than 7 days. So if something goes wrong you will need to find the vessel quickly and remove it.
Where does the antigen meet the lymphocyte?
What is a lymphocyte?
Where can you safely insert your vessel?
What path do you need to take to get your vessel to find the antibody?
STOP DO NOT GO ANY FUTHER UNTIL INSTRUCTED TO DO SO
PAGE 2
You decide that you need to be inserted into Sam’s femoral artery because the antigen/antibody challenge usually occurs in the spleen or lymphnode. The femoral artery is large enough to hold your vessel and should provide a safe entry.
1. What is the antigen/antibody challenge?
2. What/where is the spleen? Lympnode?
3. What immune responses are you likely to encounter?
4. What will be your route from the femoral artery to the spleen?
5. Once you are in the spleen how will you find the antibody necessary to fight the virus?
STOP DO NOT GO ANY FURTHUR UNTIL INSTRUCTED TO DO SO
PAGE 3
Your vessel is inserted into Sam’s femoral artery. On your view screen you see that your ship is caught in this rushing red fluid and is going much to fast. Immediately a large white blob comes after the vessel. You realize it is a Macrophage, the area around you is getting much smaller there is nowhere to hide.
1. What is a macrophage?
2. What is the rushing red fluid?
3. Why is the area around you getting smaller?
STOP DO OT GO ON TO THE NEXT PAGE UNTIL TOLD TO DO SO
PAGE 4
You have successfully escaped the macrophage but you realize you are going the wrong way. The trip from the femoral artery to the spleenic artery goes through the heart. You did not design your vessel to survive a trip through the heart, and if the vessel were to survive you could cause Sam to have a myocardial infarction. You have to figure a way to get from the femur to the spleen with out going through the heart. Maybe you can some how get out of the artery and try to get through the interstitial fluid or lymph? But how?
Oh no the area is getting crowded and a clear liquid is seeping out of the blood vessel. You also notice the area is getting warmer and redder. Maybe you are approaching a capillary. That gives you an idea.
What is lymph?
What is interstitial fluid?
Why is the area hot, red and leaking fluid?
What is a capillary?
Could you leak out? Where would you end up and how would you get to the spleen?
STOP DO NOT GO TO THE NEXT PAGE UNTIL YOU ARE TOLD TO DO SO
PAGE 5
Your task is to:
1. Explain how you are going to get out of the femoral artery without damaging it. Remember you cannot add equipment to your vessel that was not in the original plan.
Then you are to explain in detail the route you will take from the femoral artery to the spleen. And how you will enter the spleen once you get there. Be sure to include any immune response your trip will trigger and explain what each one is and how you will survive it. You explanation should be at least 1 typed page, double-spaced.
You must include at least 2 specific immune responses and 2 nonspecific immune responses.
You need to also include a “map” of the trip, including all organs, cells, blood vessels etc. that you will be travel through. The diagram needs to be large enough for the class to see during your presentation.
PAGE 5 B
For some unknown reason you have last all power. You can still track your vessel but you have no power to run machinery or propel your vessel. You must use Sam’s body to get you to the spleen.
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