Effects of Vitamin C on health: a review of evidence

Collagen synthesis. 4.2. Regulation of hypoxia-inducible factor 1α ... However most studies have linked the excessive generation of ROS, so-called oxidative stress, to disease states, such as cancer, insulin resistance, diabetes mellitus, cardiovascular diseases, atherosclerosis, and aging (39-40, 91-94) and superoxide is the most biologically ... ................
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