London School of Hygiene & Tropical Medicine
The number of T2-hyperintense brain and spinal cord lesions plus T1-hypointense brain lesions was recorded at baseline and follow-up. The lesions were identified by a single experienced neuroradiologist, who was blinded the patient’s clinical status. T2-hyperintense and T1-hypointense brain lesions were outlined using a semi-automated edge ... ................
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