Central Dogma of Genetics - California State University ...
Central Dogma of Genetics
? Within each cell the genetic information flows from
? DNA to RNA to protein.
? This flow of information is unidirectional and irreversible. ? The information carried within the DNA dictates the end product
(protein) that will be synthesized.
? This information is the genetic code.
? Conversion of DNA encoded information to RNA
? is called transcription.
? The information from a mRNA is then translated to an amino acid sequence in the corresponding protein
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Central Dogma
2
Proteins
? Building blocks are Amino acids
? AA's are joined between the carboxyl end of one AA to the amino group of the other
? One water molecule is lost ? Enzyme called peptidyl transferase is
involved
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Protein Structure
4
Fig. 14.4 Four levels of protein structure
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Peter J. Russell, iGenetics: Copyright ? Pearson Education, Inc., publishing as Benjamin Cummings.
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