Neonatal Intensive Care Drug Manual
Preterms: High dose versus low dose 1. Higher doses of 4─5 mg/kg at extended intervals of 36─48 hours confers a more favourable pharmacokinetic profile than low doses of 2.5 mg/kg 24 hourly 1,2,8-15 (Level II, Grade B). Monitoring: Target peak and trough concentrations 1. ................
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