PSYCHIATRIC DRUG DISCOVERY
John Cade discovered the sedatinf ects of lithium in 1949f rst in guineas pigs and soon thereaf er in manic patients. In the re-markably short period that followed—less than a decade—prototypes of the other major classes of psychiatric drugs were identf ed: the antipsychotic drugs (begin-ning with chlorpromazine), antidepres- ................
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