Apheresis: Basic Principles, Practical Considerations and ...
Normal Constituents Removed Coagulation factors: •Most coagulation factors are lost at the same rate •Rapidly synthesized;replacement usually is 2-3 days following exchange •Practical: measure PT/PTT/Fibrinogen every 2-3 days (rather then daily) Platelets: • 25-30% per procedure •Endogenous synthesis replaces lost platelets within 2-4 days (except hypoplastic/aplastic marrow) ................
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