ESTROGEN SESSION - CONVERSATION ON HORMONES …

The metabolism of cholesterol to 3(,5(-THP in the VTA is mediated by enzymes including some cytochrome P450 enzymes, which may be downstream factors of PXR. Expression of the PXR gene has been localized to the rat midbrain in our microarray study. In the current study, we have further localized PXR via RT-PCR and western blots. ................
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