Test systems for the diagnosis of diabetes mellitus type I

Test systems for the diagnosis of diabetes mellitus type I

Increasing likeliness of diabetes mellitus type I with rising number of different specific autoantibodies (Aab)

100

No Aab

80

1 Aab

2 Aab

3 Aab 60

Likeliness of diabetes mellitus type I (%)

40 20

0

0

5

10

15

20

Age of the patient (years)

acc. to Ziegler et. al, JAMA (2013)

The detection of several associated antibodies supports a reliable diagnosis!

IIFT: Diabetes mellitus screen, pancreas (monkey) (Order no. FA / FC 1020)

? Comprehensive and parallel analysis of all anti-islet cell antibodies ? Supports the diagnosis and diagnostic differentiation of latent autoimmune diabetes in adults (LADA)

from diabetes mellitus type II

Anti-GAD ELISA (Order no. EA 1022-9601 G)

? Detection of antibodies against glutamic acid decarboxylase (GADA) from the preclinical phase up to years after disease onset in children as well as LADA patients

Anti-IA2 ELISA (Order no. EA 1023-9601 G)

? Detection of antibodies against tyrosine phosphatase (IA2A) ? IA2A have a high diagnostic sensitivity in children and adolescents with regard to rapid progression

towards manifest diabetes mellitus type I

Anti-GAD/IA2 Pool ELISA (Order no. EA 1022-9601-1 G)

? Increased accuracy through simultaneous detection of two relevant antibodies, (GADA) and (IA2A)

Anti-Zinc transporter 8 ELISA (Order no. EA 1027-9601)

? Determination of autoantibodies against zinc transporter 8 (ZnT8A) ? ZnT8A occur in 25 % to 30 % of type 1 diabetes mellitus patients who do not exhibit other antibodies

associated with the disease

EUROIMMUN Medizinische Labordiagnostika AG ? Seekamp 31 ? 23560 L?beck (Germany) ? Phone: +49 451 20 32-0 ?

HA_1022_R_UK_B04, 07/2022

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