Glutamic Acid Decarboxylase Autoantibodies in Preclinical ...

GAD is an (auto)antigen in a majority of subjects operationally defined as having preclinical IDDM, (it) pancreatic islet and brain GAD are likely to be cross-reactive, and (iid) the majority of GAD antibodies are directed away from the catalytic site of the brain enzyme. The lower frequency of GAD antibodies in ................
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