ADAM CIEN - UPMC



Ronny Kalash, DO

Resident Physician, UPMC Hillman Cancer Center

5230 Centre Ave ● Pittsburgh, PA 15232

kalashr2@upmc.edu

Education & Training

University of Pittsburgh Hillman Cancer Center - Pittsburgh, PA

• Chief Resident - Program Director : Dr. Sushil Beriwal 2018-2019

• Resident Physician – Dept. of Radiation Oncology 2015-2019

Allegheny General Hospital – Pittsburgh, PA 2014-2015

• Internal Medicine Intern - Program Director : Dr. James B. Reilly

Lake Erie College of Osteopathic Medicine – Erie, PA 2009-2014

• Student Government Class President

• TOUCH Pin Award Recipient 2011

University of Pittsburgh – Pittsburgh, PA 2005-2009

• Bachelor of Science in Neuroscience

• Bachelor of Science in Psychiatry

• Minor Degree in Chemistry

• Certificate in Conceptual Foundations in Medicine

Certifications & Licensure

UPMC Radiation & Respiratory Motion Management Course 09/2017

UPMC Stereotactic Ablative Radiotherapy (SABR/SRS) Course 05/2016

UPMC Principles and Practices of Gamma Knife Radiosurgery Course 06/2017

Medical Training License, Commonwealth of Pennsylvania 2014-2019

National Board of Osteopathic Medicine Step I, II, and III 2010-2013

United States Medical Licensing Exam Step I, II CS/CK 2010 - 2013

Advanced Cardiac Life Support (A.C.L.S.) 2010–Present

Cardiopulmonary Resuscitation (C.P.R.) 2010 – Present

Professional Memberships

American Brachytherapy Society (ABS) 07/2014

Association of Residents in Radiation Oncology (ARRO) 07/2014

The Radiosurgery Society (RSS) 07/2014

American Society of Radiation Oncology (ASTRO) 09/2012

American College of Radiation Oncology (ACRO) 09/2012

Radiation Research Society (RRS) 09/2012

American Chemical Society (ACS) 09/2005

Awards & Honors

Cureus Case-Report Competition Winner – Exceptional SRS Outcomes 02/2018

Shadyside Hospital Foundation Research Grant 06/2017

Judith Stitt American Brachytherapy Society Abstract Award 04/2017

Peer-Reviewed Publications

1. Kalash R, Glaser SM, Rangaswamy B, Horne ZD, Kim H, House C, Beriwal S. The Use of Functional MRI in Cervical Cancer Patients with Incomplete Response on PET/CT Following Image-Based High-Dose Rate Brachytherapy. Int J Radiat Oncol Biol Phys; Accepted In Press 2018

2. Kalash R, Glaser SM, Flickinger JC, Burton S, Heron DE, Gerszten PC, Engh JA, Amankulor NA, Vargo JA. Stereotactic body radiation therapy for benign spine tumors: is dose de-escalation appropriate? Journal of Neurosurgery; Accepted in Press 2018.

3. Glaser SM, Kalash R, Bongiorni DR, Roberts MS, Balasubramani GK, Jacobs BL, Beriwal S, Heron DE, Greenberger JS. Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer. In Vivo, 2018; 32(1): 113-120.

4. Kalash R, Pifer PM, Beriwal S, Glaser SM, Vargo JA, Heron DE. Exceptional Eight-Year Response to Stereotactic Radiosurgery Monotherapy for Multiple Brain Metastasis. Cureus Case Reports 9(12):e2001. Doi:10.7759/cureus.2001.

5. Shinde A, Berhane H, Rhieu BH, Kalash R, Xu K, Goff J, Epperly MW, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Parmar K, Guinan E, Kagan V, Tyurin V, Ferris RL, Zhang X, Li S, Greeberger JS. Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd(-/-)(C57BL/6) Mice. Radiat Res., 2016; 185(2): 134-150.

6. Berhane H, Shinde A, Kalash R, Xu K, Epperly MW, Goff J, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Li S, Gao X, Greenberger JS. Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039. Radiat Res., 2014; 182(1): 35-49.

7. Kalash R, Berhane H, Au J, Rhieu BH, Epperly MW, Goff J, Dixon T, Wang H, Zhang X, Franicola D, Shinde A, Greenberger JS. Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice. In Vivo. 2014; 28(2):147-71.

8. Kalash R, Berhane H, Yang Y, Epperly MW, Wang H, Dixon T, Rhieu B, Greenberger JS, Huq MS. Improved survival of mice after total body irradiation with 10 MV photon, 2400 MU/min SRS beam. In Vivo. 2014; 28 (1): 1-12.

9. Berhane H, Epperly MW, Goff J, Kalash R, Cao S, Franicola D, Zhang X, Shields D, Houghton F, Wang H, Wipf P, Parmar K, Greenberger JS. Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice. Radiat Res. 2014; 181(1): 76-89.

10. Vargo JA, Verma V, Kim H, Kalash R, Heron DE, Johnson R, Beriwal S. Extended (5-year) outcomes of accelerated partial breast irradiation using MammoSite balloon brachytherapy: patterns of failure, patient selection, and dosimetric correlates for late toxicity. Int J Radiat Oncol Biol Phys. 2014; 88(2): 285-91.

11. Kalash R, Epperly MW, Goff J, Dixon T, Sprachman MM, Zhang X, Shields D, Cao S, Franicola D, Wipf P, Berhane H, Wang H, Au J, Greenberger JS. Amelioration of radiation-induced pulmonary fibrosis by a water-soluble bifunctional sulfoxide radiation mitigator (MMS350). Radiat Res. 2013; 180(5): 474-90.

12. Kabolizadeh P, Kalash R, Huq MS, Greenberger JS, Heron DE, Beriwal S. Dosimetric definitions of total lung volumes in calculating parameters predictive for radiation-induced pneumonitis. Am J Clin Oncol. 2015; 38(4): 401-404.

13. Vargo JA, Heron DE, Ferris Rl, Rwigema JC, Kalash R, Wegner RE, Ohr J, Burton S. Examining tumor control and toxicity after stereotactic body radiotherapy in locally recurrent previously irradiated head and neck cancers: implications of treatment duration and tumor volume. Head and Neck. 2014; 36(9):1349-55.

14. Epperly MW, Chaillet JR, Kalash R, Shaffer B, Goff J, Franicola D, Zhang X, Dixon T, Houghton F, Wang H, Berhane H, Romero C, Kim JH, Greenberger JS. Conditional radioresistance of Tet-inducible manganese superoxide dismutase bone marrow stromal cell lines. Radiat Res. 2013; 180(2): 189-204.

15. Kalash R, Berhane H, Goff J, Houghton F, Epperly MW, Dixon T, Zhang X, Sprachman MM, Wipf P, Franicola D, Wang H, Greenberger JS. Effects of thoracic irradiation on pulmonary endothelial compared to alveolar type-II cells in fibrosis-prone C57BL/6NTac mice. In Vivo. 2013; 27(3): 291-7.

16. Vargo JA, Heron DE, Ferris RL, Rwigema JC, Wegner RE, Kalash R, Ohr J, Kubicek GJ, Burton S. Prospective evaluation of patient-reported quality-of-life outcomes following SBRT +/- cetuximab for localy-recurrent, previously-irradiated head and neck cancer. Radiother Oncol. 2012; 104(1): 91-5.

17. Kim H, Bernard ME, Farkas A, Goff J, Kalash R, Houghton F, Shields D, Franicola D, Dixon T, Zhang X, Epperly M, Wang H, Cobanoglu MC, Greenberger JS. Ionizing irradiation protection and mitigation of murine cells by Carbamazepine is p53 and autophagy independent. In Vivo. 2012; 26(3): 341-54.

18. Miller DM, Reighard DA, Mehta AS, Mehta AS, Kalash R, Yates BJ. Responses of thoracic spinal interneurons to vestibular stimulation. Exp Brain Res. 2009; 195(1):89-100.

19. Lois JH, Rice CD, Mehta AS, Mehta AS, Kalash R, Yates BJ. Mapping of multisynaptic inputs from the midbrain, diencephalon, and cerebral cortex to phrenic motoneurons using transneuronal transport of rabies virus N2C in the cat. The FASEB Journal. 2008; 22(1).

Book Publications

1. Kunos C, Kalash R, Beriwal S. Gynecologic SBRT in Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy. In Press.

2. Kalash R, Engh JA, Amankulor N. Brain SRS in Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy. In Press.

Presentations (Selected)

1. Kalash R, Glaser SM, Flickinger JC, Burton S, Heron DE, Gerszten PC, Engh JA, Amankulor NA, Vargo JA. Stereotactic body radiation therapy for benign spine tumors: is dose de-escalation appropriate? Oral Presentation, RSS Annual Meeting, 11/2017 – Las Vegas, NV.

2. Kalash R, Rangaswamy B, Glaser SM, Beriwal S. The Predictive Value of Pre-Treatment ADC in Cervical Cancer Patients treated with MRI Guided High-Dose Rate Brachytherapy – Ready for Prime Time? Poster Presentation, ASTRO 2017 Annual Meeting, 09/2017 - San Diego, CA.

3. Kalash R, Glaser SM, Rangaswamy B, Horne ZD, Kim H, House C, Beriwal S. The Use of Functional MRI in Cervical Cancer Patients with Incomplete Response on PET/CT Following Image-Based High-Dose Rate Brachytherapy. Plenary Oral Presentation, ABS 2017 Annual Meeting, 04/2017 - Boston,MA

4. Kalash R, Glaser SM, Balasubramani G, Flickinger JC, Beriwal S. Adult Ependymoma: Practice Patterns and Overall Survival. Poster Presentation – ASTRO 2016 Annual Meeting, 09/2016 - Boston, MA

5. Kalash R, Berhane HW, Epperly MW, Yang Y, Dixon T, Heron DE, Greenberger JS, Huq S. Gene Transcript Responses in 10MV Photon at 2400 MU/min Total Body Irradiated C57BL/6NTac Mice Correlate with Increased Survival Compared to the Same TBI dose using 6MV Photons or Lower Dose Rates. Oral Presentation – ASTRO 2013 Annual Meeting, 09/2013 – Atlanta, GA

6. Kalash R, Berhane HW, Goff J, Dixon T, Zhang X, Epperly MW, Greenberger JS. Significant Differences in Thoracic Irradiation Induced Pulmonary Gene Transcripts between Fibrosis- Prone C57BL/6NHsd and Fibrosis- Resistant C3H/Hen Mice. Oral Presentation – ASTRO 2013 Annual Meeting, 09/2013 – Atlanta, GA.

7. Goff J, Kalash R, Dixon T, Epperly MW, Sprachman M, Zhang X, Cao S, Wipf P, Berhane HW, Greenberger JS. Late pulmonary fibrotic phase specific homing of luciferase+ bone marrow stromal cells to the irradiated C57Bl/6Hnsd mouse lung. Oral Presentation – ASTRO 2013 Annual Meeting, 09/2013 – Atlanta, GA.

8. Berhane HW, Kalash R, Epperly MW, Goff J, Franicola D, Zhang X, Shields D, Cao S, Houghton F, Greenberger JS. Radiobiologic Differences Between Bone Marrow Stromal and Hematopoietic Progenitor Cells from Fanconi Anemia (FancD2-/-) mice. Oral Presentation – ASTRO 2013 Annual Meeting, 09/2013 – Atlanta, GA.

9. Kalash R, Berhane HW, Goff J, Epperly MW, Dixon T, Shields D, Franicola D, Greenberger JS. Radiobiologic Differences between Bone Marrow Stromal and Hematopoietic Progenitor Cells from Fanconi Anemia (FancD2-/-) mice. Oral Presentation – ASTRO 2013 Annual Meeting, 09/2013 – Atlanta, GA.

10. Kalash R, Berhane HW, Goff J, Epperly MW, Dixon T, Shields D, Franicola D, Greenberger JS. Epigenetic Changes in Irradiated Murine Lung Correlate With the Onset of Late Fibrosis. Oral Presentation – ACRO 2013 Annual Meeting – San Antonio, TX.

11. Kabolizadeh P, Kalash R, Beriwal S. Dosimetric Definitions of Lung Volumes in Calculating Parameters for Radiation Induced Pneumonitis. Oral Presentation ACRO 2013 Annual Meeting – San Antonio, TX.

12. Vargo JA, Heron DE, Ferris RL, Rwigema JC, Wegner RE, Kalash R, Ohr J, Kubicek GJ, Buron S. Prospective Evaluation of Patient-Reported Quality-of-Life Outcomes Following SBRT ± Cetuximab for Locally-Recurrent, Previously-Irradiated Head-and-Neck Cancer. Oral Presentation ACRO 2012 Annual Meeting – Fort Meyers, FL.

Teaching

University of Pittsburgh School of Medicine

– Radiation Oncology Interest Group

Lecture: GI Cancers and Radiation Oncology 10/2012

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