Australian Public Assessment Report for Regorafenib
Life expectancy restrictions. ECOG or Karnofsky Performance Status (see Appendix 2) Demonstrate adequate. organ function . as defined. below. Adequate bone marrow function: leukocytes. absolute neutrophil count. platelets. Adequate hepatic function: total bilirubin. within normal institutional limits. total bilirubin. within normal institutional limits. AST(SGOT) ≤2.5 X institutional upper ... ................
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