PB07 Correlation of element concentrations, determined by IBA, with ...

PB07 Correlation of element concentrations, determined by IBA, with clinicai parameters of HIV-Aids serum specimens

M.L. Maqutu'?', JA Mars'o" C. Kunsevi-Kilola'o" M. Saayman'O', S. Tarro" A. Mohammed'?'

'?'HIV-Aids Unit, Cape Peninsula Universily of Technology, PO Box 1906, Bellville, 7535, South Africa ,o'Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, PO Box 1906, Bellville, 7535, South Africa. 'C'National Health Training College, Private Bag A18, Maseru, Lesotho.

The economic burden of HIV-Aids related death of many individuais, especially those that are economicallyactive, has crippled many countries' economies. More so is the fact that the pathogenesis of human immuno-deficiency virus (HIV) infection is until present not fully understood. To define the pathogenesis, various clinicai parameters such as AST, ALT, LDH, billirubin, uric acid, creatinine, CPK, ALP etc, and specific parameters such as CD4 cell counts have been determined. The ions of elements such as Ca, Mg, Fe, Cu, Zn and Se are incorporated into the structure ofmanyenzymes and are therefore essential to the enzyme function. The focus ofthis study is the correlation oftrace element concentrations, determined by IBA, with the clinicai parameters.

Blood obtained from 100 HIV sero-positive males and females attending clinics at the National Health Training College in Maseru metropolis, Lesotho.

The clinicai parameters were determined by using Arkray instrumentation . Afterwards the serum specimens were freeze-dried and then pulverized into palettes. The palettes were coated with carbon and then irradiated with a proton beam of 3 MeV energy. X-ray emission and backscattering data were obtained and then quantified with various computational software.

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