PHARMACOLOGY BASIC PRINCIPLES
Codeine: 30-60mg Dosing Interval 8hrly methadone Absorption Bioavailability Morphine: 25% PO, 100% IV. Methadone: 40-80%. Fentanyl: 92% transdermal, 50% buccal. Codeine: 90% PO Half life Morphine: 2-3hrs. Methadone: 25-52 hrs (varies greatly due to enzyme differences) Fentanyl: 3-12hrs. Codeine: 2.5 – … ................
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