Recent Advances in Assessment and Management of ...
[Pages:70]Recent Advances in Assessment and Management of Chemotherapy Toxicities
in Elderly
Yiwu Jim Huang, MD, PhD Division of Hematology/Oncology
Maimonides Cancer Center
Up to 30% chances reaching 100 in people born in 2011
Cancer is the Leading Cause of Death in elderly
What is different about older patients?
? Heterogeneity of health status ? Physiologic changes ? Increased prevalence of disease ? Tendency to have multiple, often interacting, diseases ? Under-reporting of symptoms ? Atypical presentation of common illnesses ? Increased importance of social support ? Increased rates of adverse effects to medications and
therapies ? Different goals of therapy
Balancing the risk and benefit in Decision Making
Benefit
Risk
Decision making
Assessment of the elderly with cancers
? Gross estimate of life expectancy and treatment tolerance
? Identification and reversal of conditions that may hamper treatment - comorbidity, lack of caregiver, subclinical dementia, depression, et al.
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