Sveikas Žmogus
Ovarian cancer
Globally, ovarian cancer is the most deadly of the gynaecological cancers1
Ovarian cancer is diagnosed in nearly a quarter of a million women globally each year.
It is the eighth most common and the seventh leading cause of cancer death among women, responsible for approximately 140,000 deaths each year.
Many patients are diagnosed late, when treatment becomes more difficult
The prognosis for ovarian cancer patients is poor and over half of women diagnosed with ovarian cancer will not live beyond five years.2,3
Symptoms are ambiguous and often misdiagnosed4,5 as they can be confused with symptoms of other less severe diseases, particularly gastrointestinal complaints.
This means the majority of patients
are only identified in the advanced stages when the disease becomes more difficult to treat.2
In addition, there is no routine, simple test to accurately detect ovarian cancer so reliable screening for the disease is not yet feasible.6
For this reason, ovarian cancer is often referred to as “The Silent Killer”.
Treatment options include surgery, chemotherapy and biological therapies
Treatment options vary depending on the size, position and stage of the cancer as well as the patient’s physical condition.
There have been few treatment advances in several years. Surgery and chemotherapy remain the current standard of care.
In most cases of advanced ovarian cancer initial treatment (with surgery and chemotherapy) does not stop the disease returning and most women will have a relapse within 15 months of diagnosis.7
References
1. WHO, IARC GLOBOCAN, Cancer Incidence and Mortality Worldwide in 2008 at
2. Heintz APM, Odicino F, Maisonneuve P, et al. Int J Gynaecol Obstet 2006;95 (Suppl 1):S161–92
3. American Cancer Society. Cancer Facts and Figures 2007. Atlanta, American Cancer Society 2007
4. Goff BA, Mandel L, Muntz HG, Melancon CH. Cancer 2000;89:2068–75
5. Goff BA, Mandel L, Melancon CH, Muntz HG. JAMA 2004;291:2705–12
6. Badgwell D, Bast RC. Markers 2007;23:397–410
7. Hennessy B et al. Lancet 2009; 9698: 1371-1382
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Figure 2 Annual incidence and mortality rates of female cancers worldwide
Figure 1 Age standardised mortality rate for ovarian cancer
Figure 3 Late diagnosis results in poor survival
Figure 3 Late diagnosis results in poor survival
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