ANCA-Associated Vasculitis in 2021: Where Are We Now, and Where Are We ...
ANCA-Associated Vasculitis in 2021: Where Are We Now, and Where Are
We Going?
Andrew S. Bomback, MD, MPH Associate Professor of Medicine Director of Clinical Research, Division of Nephrology Columbia University College of Physicians and Surgeons
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? I am a consultant for Chemocentryx
Outline
? Clinical presentation ? Classification schemes ? Treatment ? moving away from the traditional route
? Induction
? Steroids ? low dose? ? PLEX ? should we use for renal failure? ? Cytoxan ? should we use rituximab?
? Maintenance
? AZA vs. MMF ? or should we use rituximab?
? Complement blockade in treating ANCA ? an even newer route?
Clinical presentation
Clinical presentation
? Pearl: ANCA can present any $#@&-ing way it pleases
? Most common presenting symptom: "I just don't feel right."
? Vasculitis symptoms: Flu-like symptoms including fever, body aches, joint and muscle pain, reduced appetite, and weight loss.
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