Section 4: Vaccine Safety Public Health and Clinical ...
smallpox An acute eruptive contagious disease caused by a poxvirus (Orthopoxvirus, a member of the family Poxviridae) and marked at the onset by chills, high fever, backache, and headache; in 2–5 days the constitutional symptoms subside and an eruption appears as papules, which become umbilicated vesicles, develop into pustules, dry, and form ... ................
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