Regulatory Status of Caffeine - NIH Office of Dietary ...
Regulatory Status of Caffeine
Antonia Mattia, Ph.D. Director, Division of Biotechnology and GRAS Notice Review
CFSAN/Office of Food Additive Safety
The Use and Biology of Energy Drinks: Current Knowledge and Critical Gaps National Institutes of Health, August 15-16, 2013 Neuroscience Center Building, Rockville, MD
Outline
Explain GRAS as it relates to food ingredients Review caffeine's regulatory status and history Describe FDA's current concerns re: safety Summarize FDA's work leading up to the recent
IOM workshop on caffeine Discuss potential next steps
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Caffeine
Naturally present in coffee, tea, chocolate, and the cola nut extract used in cola-type beverages
1, 3, 7-trimethylxanthine Long history of safe use
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Foods or dietary supplements?
Energy drinks marketed as
"foods"
? Subject to FD&C Act
? Ingredients: approved food additives or GRAS for their intended uses
Energy drinks marketed as
"dietary supplements"
? Subject to DSHEA
? Must be labeled as dietary supplements
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Definition of "food additive"
"...any substance the intended use of which
results or may reasonably be expected to result, directly or indirectly, in its becoming a component or otherwise affecting the characteristics of any food...if such substance is not generally recognized, among experts qualified by scientific training...to be safe under the conditions of its intended use..."
(FD&C Act Section 201(s))
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