THE BEST ANTIBIOTIC SENSITIVITY CHART EVER (at least the ...
[Pages:1]THE "BEST" ANTIBIOTIC SENSITIVITY CHART EVER (at least the best we could make)
Bacteria
Streptococci
Gram Positive Cocci Staphylococci
Streptococci (pneumoniae/
pyogenes/ viridans group)
Enterococci (Group D strep)
Staph epidermidis (coagulase
negative)
Staph aureus (Methicillin sensitive)
Community acquired (Methicillin resistant)
Hospital acquired (Methicillin resistant)
Created by James McCormack, BSc(Pharm), PharmD and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP with assistance from Tim Lau Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC
Gram Negative Bacilli
Non-beta-lactamase producing Escherichia coli,
Klebsiella pneumoniae, Haemophilus influenzae
SPACE
ESBL
Beta-lactamase producing Escherichia coli,
Serratia marcescens,
(Extended spectrum beta-lactamase
Klebsiella pneumoniae, Haemophilus influenzae
Proteus mirabilis, Acinetobacter sp.,
Citrobacter sp.,
producing) Escherichia coli, Klebsiella pneumoniae
Enterobacter sp.
CRE (Carapenem-resistant Enterobacteriaceae)
Pseudomonas aeruginosa
Gram Negative Coccobacilli
Neisseria meningitidis
Neisseria gonorrhea
Anaerobes
Atypicals
Above the diaphragm (Peptostreptococcus)
Below the diaphragm (Bacteroides sp)
Clostridium difficile
Mycoplasma pneumoniae, Chlamydophila
spp
Legionella pneumophila
Chlamydia trachomatis
Location
Penicillins
Cephalosporins
Brain, oral, respiratory tract,
Intraabdominal,
heart, skin
urinary tract
Pencillin V/G Amoxicillin/ampicillin
Amoxicillin-clavulanate Piperacillin-tazobactam Cefazolin/cephalexin Cefuroxime Cefoxitin Ceftriaxone/cefotaxime Cefixime
Skin, prosthetics
Oral, respiratory tract, heart, skin, bones/joint
Cloxacillin Amoxicillin-clavulanate Piperacillin-tazobactam Cefazolin/cephalexin Cefuroxime Cefoxitin Ceftriaxone/cefotaxime
Carbapenems Macrolides Tetracyclines
Cefipime Ceftibiprole
Meropenem/imipenem/doripenem Ertapenem Erythromycin Clarithromycin/azithromycin Tetracycline/doxycycline
Cefipime
Meropenem/imipenem/doripenem Ertapenem Erythromycin
Clarithromycin/azithromycin Tetracycline/doxycycline
Ceftibiprole Tigecycline
Fluoroquinolones
Levofloxacin/moxifloxacin
Aminoglycosides
Polymyxin
Lincosamides
Clindamycin
Clindamycin
Glycopeptides/lipoglycopeptides
Vancomycin/daptomycin
Oxazolidinones
Linezolid/tedizolid
Trimethoprim-Sulfamethoxazole
Trimethoprim-sulfamethoxazole
Chloramphenicol
Chloramphenicol
Metronidazole
Nitrofurantoin/fosfomycin
Nitrofurantoin/fosfomycin
(JUST BLADDER INFECTIONS)
JUST E.faecalis
Rifampin
Rifampin
Fidaxomicin
Cloxacillin and clindamycin typically have less than 40% activity for S.epidermidis, thus usage depends on local susceptibility data Enterococci has two main species - Enterococcus faecalis and Enterococcus faecium; the antibiotics listed are active against E.faecalis, but have limited activity for E.faecium
Cephalosporins have in-vitro activity for SPACE organisms but induce production of beta-lactamases
Tigecycline has no activity against Pseudomonas aeruginosa, but for Acinetobacter it depends on local susceptibility data; Tigecycline is active against SPACE organisms, but for Proteus spp it depends on local susceptibility data
Brain, respiratory tract, intraabdominal, urinary tract
Amoxicillin/ampicillin
Amoxicillin-clavulanate Piperacillin-tazobactam
Cefazolin/cephalexin Cefuroxime Cefoxitin
Ceftriaxone/cefotaxime Cefixime
Ceftazidime Ceftolozane - tazobactam
Cefipime
Meropenem/imipenem/doripenem Ertapenem
Clarithromycin/azithromycin JUST H.flu Tetracycline/doxycycline JUST H.flu
Ciprofloxacin/norfloxacin BUT JUST bladder infections for norfloxacin Levofloxacin/moxifloxacin Gentamicin/tobramycin/amikacin
Colistin/polymyxin B
Trimethoprim-sulfamethoxazole Chloramphenicol
Nitrofurantoin/fosfomycin
Nitrofurantoin/fosfomycin
Brain
Pencillin G-IV Ampicillin-IV
Pelvic inflammatory disease/STI
Oral, respiratory tract
Pencillin V/G Amoxicillin/ampicillin
Intraabdominal, pelvic inflammatory disease
Intraabdominal
Piperacillin-tazobactam
Ceftazidime Ceftolozane-tazobactam
Cefipime
Ceftriaxone/cefotaxime Cefixime
Amoxicillin-clavulanate Piperacillin-tazobactam
Cefazolin/cephalexin Cefuroxime Cefoxitin
Ceftolozane-tazobactam Cefipime
Meropenem/imipenem/doripenem
Meropenem/imipenem/doripenem Ertapenem
JUST Azithromycin
Tetracycline/doxycycline Tigecycline
Gentamicin/tobramycin/amikacin Colistin/polymyxin B
Levofloxacin/moxifloxacin
JUST Moxifloxacin
Clindamycin Vancomycin/daptomycin
Linezolid/tedizolid
Vancomycin oral
Chloramphenicol
Metronidazole
Respiratory tract
Pelvic inflammatory disease/STI
Erythromycin
Clarithromycin/azithromycin
JUST Azithromycin
Tetracycline/doxycycline
Tigecycline
JUST Ciprofloxacin
Levofloxacin/moxifloxacin
Rifampin
Fidaxomicin
NOVEMBER 2019
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